Results 31 to 40 of about 755 (259)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Comparative Analysis of Grid-Following (GFL) and Grid-Forming (GFM) Inverters: Control and Transition Capabilities

Electrical Engineering and Energy
In recent years, interest in integration of renewable energy (RE) sources (particularly Wind Energy Systems - WES) into the electrical grid for sustainable, innovative solutions and a greener future continues to grow exponentially.
Fatih Burak, Hulusi Karaca
doaj   +1 more source

Understanding the Stochastic Nature of Process Parameter Development of Blown Powder Laser Beam Directed Energy Deposition Additive Manufacturing of Pure Molybdenum

Advanced Engineering Materials, EarlyView.
Identified through the use of statistical design of experiments and metallographic investigation, this study exposes the stochastic origins of intergranular cracks in blown powder laser beam directed energy deposition additive manufacturing of pure molybdenum. It further demonstrates a successful crack mitigation approach with direct correlation to the
Nathaniel J. Lies, Daniel E. Driemeyer, Aaron P. Stebner   +2 more
wiley   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Reduced-Order Modeling and Stability Analysis of Grid-Following and Grid-Forming Hybrid Renewable Energy Plants

Energies
The control methods of energy systems can be categorized into grid-following and grid-forming types. The grid-following control method relies on grid synchronization and is prone to stability issues in weak grid conditions.
Yue Ma, Ning Chen, Luming Ge
doaj   +1 more source

On the Effect of Creep on Local Lattice Orientation in Single‐Crystal Ni‐Based Superalloy Microstructures

Advanced Engineering Materials, EarlyView.
During creep of a single‐crystal Ni‐based superalloy, the overall crystal orientation is observed to remain constant while the microstructure evolves. Despite the lack of macroscopic rotation, small (<1°) rotations are observed on the submicron size scale and are accommodated by counteracting rotations over the scale of several micrometers.
E. J. Payton, E. B. Dursun, G. Eggeler, L. Agudo Jácome   +3 more
wiley   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

Advanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein, Tiago Carneiro Gomes, Eliza Ng, Simon Rondeau‐Gagné, Tricia Breen Carmichael   +4 more
wiley   +1 more source

Demonstrating Vibrational Current Generation With a Self‐Assembled Bioelectret

Advanced Functional Materials, EarlyView.
Vacuum‐deposited films of the plant‐derived molecule, Baicalein, form a self‐assembled bioelectret exhibiting spontaneous orientation polarization and a giant surface potential. The films induce alternating current during the vibration of a movable electrode without charging treatments. Hydrocarbon protection enhances the air stability of the Baicalein
Kouki Akaike, Yukihiro Shimoi, Qingshuo Wei, Yutaro Ono, Satomi Hosono, Yoichi Yamada, Haruhisa Akiyama, Shunsuke Tanaka   +7 more
wiley   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

Modeling Lyapunov Control-Based Selective Harmonic Compensated Single-Phase Inverter in the Dynamic Phasor Domain

IEEE Open Journal of Industry Applications, 2023
Single-phase grid-forming inverters are commonly used in uninterruptible power supply (UPS) systems that feed single-phase critical loads in homes, data centers, and hospitals.
Udoka C. Nwaneto, Seyed Ali Seif Kashani, Andrew M. Knight   +2 more
doaj   +1 more source