Results 81 to 90 of about 12,675,276 (305)

A model combining oscillations and attractor dynamics for generation of grid cell firing

Frontiers in Neural Circuits, 2012
Different models have been able to account for different features of the data on grid cell firing properties, including the relationship of grid cells to cellular properties and network oscillations. This paper describes a model that combines elements of
Michael E Hasselmo, Mark P. Brandon
doaj   +1 more source

Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map

IEEE Access, 2021
A Biomimetic SLAM Algorithm Based on Growing Self-Organizing Map (GSOM-BSLAM), inspired by spatial cognitive mechanism of mammalian hippocampus, is proposed to resolve uncertainty problems in location identification and lack of real-time performance in ...
Yukun Zhang, Mengyuan Chen, Dehong Tian, Lingmei Ding   +3 more
doaj   +1 more source

Replay as wavefronts and theta sequences as bump oscillations in a grid cell attractor network. [PDF]

, 2019
Grid cells fire in sequences that represent rapid trajectories in space. During locomotion, theta sequences encode sweeps in position starting slightly behind the animal and ending ahead of it. During quiescence and slow wave sleep, bouts of synchronized
Ambrose, Anderson, Angulo-Garcia, Azizi, Bayati, Belchior, Bonnevie, Brandon, Burak, Burgess, Bush, Buzsáki, Buzsáki, Buzsáki, Buzsáki, Chance, Cheng, Chenkov, Chrobak, Chrobak, Climer, Colgin, Couey, Davidson, Diba, Diehl, Dragoi, Drieu, Dunn, Ebbesen, English, Evans, Feng, Foster, Foster, Foster, Fuchs, Gonzalez-Sulser, Grosmark, Gu, Gönner, Hafting, Hafting, Haga, Hahn, Hales, Hardcastle, Hasselmo, Heys, Hollup, Jeewajee, Johnson, Kang, Keinath, Kempter, Kerr, Koenig, Lee, Leutgeb, Liu, Liu, Mamad, Middleton, Navratilova, Nolan, O'Keefe, O'Keefe, O'Keefe, O'Neill, Ocko, Oliva, Palmer, Palmer, Pfeiffer, Pfeiffer, Ponulak, Ramirez-Villegas, Raudies, Reifenstein, Reifenstein, Sargolini, Sasaki, Savelli, Schlesiger, Schlingloff, Schmidt, Silva, Simon, Singer, Skaggs, Stark, Stensola, Steriade, Thurley, Thurley, Trimper, Tsodyks, Unal, Urdapilleta, Vanderwolf, Vinogradova, Widloski, Wikenheiser, Wikenheiser, Wilson, Winterer, Wu, Wu, Xu, Yamaguchi, Yamamoto, Yoon, Yoshida, Zhang, Zheng, Zielinski, Zutshi, Ólafsdóttir, Ólafsdóttir, Ólafsdóttir   +119 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Smart grids for rural conditions and e-mobility - Applying power routers, batteries and virtual power plants [PDF]

, 2016
Significant reductions of greenhouse gas emission by use of renewable energy sources belong to the common targets of the European Union. Smart grids address intelligent use and integration of conventional and renewable generation in combination with ...
Boehner, Volker, Franz, P., Gallart, R, Girbau Llistuella, Francesc, Hanson, J., Martínez, S., Sumper, Andreas   +6 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

eLife
Spatial periodicity in grid cell firing has been interpreted as a neural metric for space providing animals with a coordinate system in navigating physical and mental spaces.
Rebecca RG, Giorgio A Ascoli, Nate M Sutton, Holger Dannenberg   +3 more
doaj   +1 more source

What grid cells convey about rat location [PDF]

, 2008
We characterize the relationship between the simultaneously recorded quantities of rodent grid cell firing and the position of the rat. The formalization reveals various properties of grid cell activity when considered as a neural code for representing ...
Brookings, Ted, Burak, Yoram, Fiete, Ila R.   +2 more
core  

Coordinated grid and place cell replay during rest [PDF]

, 2016
Hippocampal replay has been hypothesized to underlie memory consolidation and navigational planning, yet the involvement of grid cells in replay is unknown.
BE Pfeiffer, BL McNaughton, C Barry, Caswell Barry, CF Doeller, CN Boccara, D Bush, D Marr, DJ Foster, E Pastalkova, F Sargolini, Francis Carpenter, H Freyja Ólafsdóttir, HF Ólafsdóttir, JJ Chrobak, MA Wilson, RF Langston, T Hafting, TJ Wills   +18 more
core   +1 more source

Modeling grid fields instead of modeling grid cells [PDF]

, 2018
A neuron’s firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal’s position in space, defining ‘grid fields ...
Rosay, Sophie, Weber, Simon N., Mulas, Marcello   +2 more
openaire   +1 more source