Results 41 to 50 of about 175,388 (261)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
DESIGNING COMPUTATIONAL GRIDS USING BEST PRACTICES IN SOFTWARE ARCHITECTURE
Journal of ICT, 2007 The basic principle of sharing and collaborative work by geographically separated computers is known by several names such as meta computing, scalable computing, cluster computing, internet computing and this has today metamorphosed into a new term known
Hema Prem, N.R. Srinivasa Raghavan
doaj
Echo: An Edge-Centric Code Offloading System With Quality of Service Guarantee
IEEE Access, 2019 Code offloading is a promising way to accelerate mobile applications and reduce the energy consumption of mobile devices by shifting some computation to the cloud.
Li Lin +4 more
doaj +1 more source
Modification and Migration of Components of the Grid-Site
Современные информационные технологии и IT-образование, 2021 All components of a grid site are interconnected by a number of tasks - to securely receive, process, store and transmit data, as well as meet certain requirements for the software of grid sites that are in the pool of large international experiments ...
Aleksey Bondyakov, Andrey Kondratyev
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Software Systems Implementation and Domain-Specific Architectures towards Graph Analytics
Intelligent Computing, 2022 Graph analytics, which mainly includes graph processing, graph mining, and graph learning, has become increasingly important in several domains, including social network analysis, bioinformatics, and machine learning.
Hai Jin +20 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Computational GRIDs and Online Laboratories [PDF]
Electronic Workshops in Computing, 2005 Many projects addressing the creation of online laboratories have been developed recently. They have a common goal: to enable students and professional learners to get hands-on experience without moving from the places where they are. Nevertheless, the found solutions are often very different among them, and interoperability between different online ...
Andrea Bagnasco +2 more
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
A simple grid implementation with Berkeley Open Infrastructure for Network Computing using BLAST as a model [PDF]
PeerJ, 2016 Development of high-throughput technologies, such as Next-generation sequencing, allows thousands of experiments to be performed simultaneously while reducing resource requirement.
Watthanai Pinthong +3 more
doaj +2 more sources