Results 31 to 40 of about 3,693,146 (236)

Optimizing Decision Tree and Random Forest with Grid Search and SMOTE for Malware Classification on IoT Network Traffic

open access: yesJournal of Applied Informatics and Computing
The rapid growth of the Internet of Things (IoT) has increased the risk of malware attacks, posing serious threats especially to micro, small, and medium enterprises (MSMEs) that often lack sufficient cybersecurity resources.
Muhammad Nurus Siroj   +2 more
doaj   +1 more source

Optimization and Validation of Two Machine Learning Algorithms for Accurate Prediction of Irrigated Wheat (Triticum aestivum L.) Yield and Identification of its Influential Factors in Khorasan Razavi Province [PDF]

open access: yesپژوهشهای زراعی ایران
IntroductionThis study undertook a detailed comparison of two supervised machine-learning algorithms—Random Forest (RF) and eXtreme Gradient Boosting (XGBoost)—to predict irrigated wheat (Triticum aestivum L.) yield across 20 counties in Razavi Khorasan ...
M Jahan
doaj   +1 more source

HS–GS: A Method for Multicenter MR Image Standardization

open access: yesIEEE Access, 2020
The access to and sharing of medical image data is essential to accelerate the research progress of complex diseases and sudden disease outbreaks. Multicenter image data is collected from different medical institutions, and the contrast and brightness of
Guohua Zhao   +7 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Grid-search method for short-term over long-term average parameter tuning: an application to Stromboli explosion quakes

open access: yesFrontiers in Earth Science
The collection of a significant catalogue of seismo-volcanic data involves the selection of relevant parts of raw signals, which can be automatised by using the short-term over long-term average (STA/LTA) method.
Andrea Di Benedetto   +6 more
doaj   +1 more source

Hyperparameter Optimization of CNN for Map Building

open access: yesСовременные информационные технологии и IT-образование, 2020
This article describes an approach for solving the task of finding hyperparameters of an artificial neural network, which is used for making a 2D land map.
Alexandra Akinina, Mikhail Nikiforov
doaj   +1 more source

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