Results 41 to 50 of about 984,534 (293)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Hyperparameter Tuning on Classification Algorithm with Grid Search
SISTEMASI, 2022 Currently, machine learning algorithms continue to be developed to perform optimization with various methods to produce the best-performing model. In Supervised learning or classification, most of the algorithms have hyperparameters. Tuning hyperparameter is an architecture of deep learning to improve the performance of predictive models.
Wahyu Nugraha, Agung Sasongko
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Search for the end of a path in the d-dimensional grid and in other graphs [PDF]
, 2015 We consider the worst-case query complexity of some variants of certain \cl{PPAD}-complete search problems. Suppose we are given a graph $G$ and a vertex $s \in V(G)$.
Gerbner, Dániel +4 more
core +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Symmetry-Based Search Space Reduction For Grid Maps [PDF]
, 2011 In this paper we explore a symmetry-based search space reduction technique which can speed up optimal pathfinding on undirected uniform-cost grid maps by up to 38 times.
Botea, Adi +2 more
core
Advanced Engineering Materials, EarlyView.Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
Machine Learning Techniques and Recommender Systems for Large Educational Data [PDF]
مجلة جامعة الانبار للعلوم الصرفةE-learning approaches allow learners with a range of courses on online platforms to choose appropriate courses according to their preferences and interests.
Ammar Mohammed, Murtadha Hamad
doaj +1 more source
Search Interfaces for Mathematicians
, 2014 Access to mathematical knowledge has changed dramatically in recent years, therefore changing mathematical search practices. Our aim with this study is to scrutinize professional mathematicians' search behavior. With this understanding we want to be able
A. Kohlhase +6 more
core +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source