Results 111 to 120 of about 370,951 (288)

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan   +10 more
wiley   +1 more source

Performance Evaluation of PI and Fuzzy Logic Controllers for a Bidirectional Buck-Boost DC/DC Converter in V2G and G2V Applications

open access: yesJournal of Machine Engineering
This paper presents a comparative analysis of a linear proportional-integral controller and a nonlinear fuzzy logic controller for a bidirectional buck-boost converter in onboard chargers for vehicle-to-grid and grid-to-vehicle applications.
Hamza El-Hassouni   +3 more
doaj   +1 more source

Bidirectional vehicle-to-grid interface under a microgrid project [PDF]

open access: yes, 2014
In the emergent deployment of smart grids, storage systems play an important role into assets utilization optimization, providing backup power and peak-shaving. This concept becomes more critical in the context of microgrids with a high penetration of
Batista, José   +2 more
core  

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Investigating the Impact of E-Mobility on Distribution Grids in Rural Communities: A Case Study

open access: yesEnergies
Germany’s energy transition to a higher share of renewable energy sources (RESs) is characterized by decentralization, with citizens, cooperatives, SMEs, and municipalities playing a central role.
Marcus Brennenstuhl   +3 more
doaj   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

open access: yesAdvanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su   +16 more
wiley   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Efficient energy management and cost optimization using multi-objective grey wolf optimization for EV charging/discharging in microgrid

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy
The depletion of conventional energy sources coupled with the rising demand for electric vehicles (EVs) has significantly underscored the necessity for electric vehicle supply equipment (EVSE) with advanced energy supply management within microgrids ...
Swati Sharma, Ikbal Ali
doaj   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

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