Results 61 to 70 of about 311,448 (302)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Anthropometry based prediction of dominant hand grip strength in Indian office going females
Background: Physical strength can be measured by means of hand grip strength. It is of great use as a functional index of nutritional status. Aims and Objectives: Physical strength can be measured by means of hand grip strength.
S Rawat
doaj +1 more source
The Alcoa ram fastener: A reusable blind rivet [PDF]
Results of tensile, shear, fatigue and accelerated weathering tests are presented for the ram fastener, a reusable, single unit blind rivet. The effects of variations in hole size, grip length and sheet thickness on strength properties of the fastener ...
Dewalt, W. J.
core +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A three-dimensional finite element model of maximal grip loading in the human wrist [PDF]
The aim of this work was to create an anatomically accurate three-dimensional finite element model of the wrist, applying subject-specific loading and quantifying the internal load transfer through the joint during maximal grip.
Bransby-Zachary, M. +7 more
core +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Measuring the Speed of Aging across Population Subgroups [PDF]
People in different subgroups age at different rates. Surveys containing biomarkers can be used to assess these subgroup differences. We illustrate this using hand-grip strength to produce an easily interpretable, physical-based measure that allows us to
Dowd, Jennifer Beam +2 more
core +1 more source
Contribution of the ulnar digits to grip strength
PURPOSE To determine the contribution of ulnar digits to overall grip strength. SUBJECTS Fifty individuals (25 men and 25 women; 100 hands) with a mean age of 35.6 years (range 19 to 62 years) were tested. Exclusion criteria included previous history of hand injuries, entrapment neuropathies and systemic diseases.
Jennifer, Methot +2 more
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Grip strength is seen as an objective indicator of morbidity and disability. However, empirical knowledge about trends in grip strength remains incomplete.
Johannes Beller +5 more
doaj +1 more source

