Results 81 to 90 of about 177,385 (295)
Nature and timing of Late Mississippian to Mid-Pennsylvanian glacio-eustatic sea-level changes of the Pennine Basin, UK [PDF]
The Pennine Basin of northern England contains a comparatively complete Serpukhovian– Moscovian succession characterized by high-resolution ammonoid zonation and cyclic paralic sedimentation.
Condon, Daniel J., Waters, Colin N.
core +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Independent measurement of the top quark mass and the light- and bottom-jet energy scales at hadron colliders [PDF]
A method for the simultaneous determination of the energy scales for b-quark jets and light jets, the jet energy resolution, and the top quark mass at hadron colliders is presented.
A. Abulencia +8 more
core +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
A look at grit: a study about Malaysian technical instructors’ performance retention [PDF]
The improvement of instructors' professionalism and quality should be prioritised to achieve Malaysia's Education Blueprint 2013-2025 goals. Most previous studies suggest that teacher effectiveness and performance retention could be measured by the ...
Abd Aziz, Azlihan +4 more
core
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Commonly, native chicken is raised in an extensive management system. The chickens were free toscavenge in the backyard, and eat a wide variety of feeds including, rice, corn, insects, or even grit.
Cytske Sabuna +2 more
doaj
Lepton anomalous magnetic moments from twisted mass fermions
We present our results for the leading-order hadronic quark-connected contributions to the electron, the muon, and the tau anomalous magnetic moments obtained with four dynamical quarks.
Burger, Florian +3 more
core +1 more source
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source

