Results 71 to 80 of about 79,883 (290)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The Brightest Part of the Forest: A Grit Analysis of an Ontario Children’s Book Award

Language and Literacy: A Canadian Educational e-journal, 2020
This study explores how grit manifests in the nominees of Ontario’s Forest of Reading Blue Spruce Award children’s literature competition from 2013-2018.
Jen McConnel, Clarissa de Leon
doaj   +1 more source

Physical activity and self-efficacy in college students: the mediating role of grit and the moderating role of gender

PeerJ
Background There is a paucity of knowledge concerning the psychological variables that serve to facilitate the connection between physical activity and self-efficacy, and the factors capable of moderating these pathways.
Hongyan Yu, Tingfei Zhu, Jianing Tian, Gang Zhang, Peng Wang, Junxiong Chen, Liqun Shen   +6 more
semanticscholar   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Wpływ akcesji Polski do UEM na funkcjonowanie polskich przedsiębiorstw w aspekcie planowania działań sprzedażowych

Problemy Zarządzania, 2012
W artykule przedstawiono, z punktu widzenia teorii i praktyki badawczej, problematykę sposobów przygotowywania się polskich firmy do podejmowania działań sprzedażowych w warunkach przyjęcia przez Polskę waluty euro.
Mgr Klaudia Pujer
doaj  

Predictors of grit among medical students: a study at a Malaysian Public University

BMC Medical Education
Background Previous literature has demonstrated associations between grit and positive educational and psychological outcomes, such as higher academic grades, lower attrition rates in medical training, and protection from burnout. However, the predictors
Nurfauzani Ibrahim, Mariam Mohamad, Suraya Abdul-Razak, Mohamed-Syarif Mohamed-Yassin, Noorhida Baharudin   +4 more
doaj   +1 more source

Exploring the roles of ideal L2 writing self, growth L2 writing mindset, and L2 writing grit in L2 writing achievement among EFL learners

Studies in Second Language Acquisition
Considering the undeniable importance of examining the role of domain- and skill-specific individual difference factors in second-language (L2) writing research, this study examined the possible roles of English-as-a-foreign-language (EFL) learners ...
J. Fathi, M. Pawlak, S. Hejazi
semanticscholar   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Relationship between maternal grit and effortful control among 18–21-month-old toddlers

Frontiers in Psychology
Grit is known to be effective for long-term academic and social success. However, few studies have focused on the role of grit in parenting and its effect on the development of grit in children.
Awoun Jung, Awoun Jung, Mikako Ishibashi, Yuta Shinya, Shoji Itakura   +4 more
doaj   +1 more source