Results 51 to 60 of about 43,378 (286)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Assessing construct validity of the Grit-S in Chinese employees.

PLoS ONE, 2018
This research examined the psychometric properties and construct validity of the Short Grit Scale (Grit-S) in Chinese insurance employees (N = 2,363; 37% males; mean age = 35.14).
Chuxian Zhong, Meng-Cheng Wang, Yiyun Shou, Fen Ren, Xintong Zhang, Mingshu Li, Wendeng Yang   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Resilience and personality traits predict nurturing grit through student effort and interest in Ghanaian higher education

Discover Psychology
The relationship between grit and academic achievement is well documented. However, the determinants of students’ grit remain elusive, particularly in resource-constrained higher education systems.
Akoto-Baako Hansen, Jotham Prem Heeralal, Dennis Ntokozo Ndwandwe   +2 more
doaj   +1 more source

The Brightest Part of the Forest: A Grit Analysis of an Ontario Children’s Book Award

Language and Literacy: A Canadian Educational e-journal, 2020
This study explores how grit manifests in the nominees of Ontario’s Forest of Reading Blue Spruce Award children’s literature competition from 2013-2018.
Jen McConnel, Clarissa de Leon
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Beyond Words: Understanding Grit in Survivors of Stroke and Caregivers

Journal of Patient Experience, 2020
Grit is defined as perseverance and long-term focus on goals. Grit may be helpful in surviving stroke for both survivors and caregivers. The purpose of this study was to investigate the level of grit among survivors of stroke and caregivers using health ...
Susan G Klappa PT, MPT, PhD, MA, Brian Quach PT, DPT, Jorden Steele PT, DPT, MS, Chelsea Harper PT, DPT   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Predictors of grit among medical students: a study at a Malaysian Public University

BMC Medical Education
Background Previous literature has demonstrated associations between grit and positive educational and psychological outcomes, such as higher academic grades, lower attrition rates in medical training, and protection from burnout. However, the predictors
Nurfauzani Ibrahim, Mariam Mohamad, Suraya Abdul-Razak, Mohamed-Syarif Mohamed-Yassin, Noorhida Baharudin   +4 more
doaj   +1 more source