Results 121 to 130 of about 4,151 (197)
Role of G protein‐coupled receptor kinases (GRKs) in β2‐adrenoceptor‐mediated glucose uptake
Truncation of the C‐terminal tail of the β2‐AR, transfection of βARKct or over‐expression of a kinase‐dead GRK mutant reduces isoprenaline‐stimulated glucose uptake, indicating that GRK is important for this response.
Seungmin Ham +9 more
doaj +1 more source
What is ‘relational thinking’, and how does it manifest in research?
Abstract People and Nature is a ‘journal of relational thinking’. This editorial explores what relational thinking can mean and how it might be operationalized in the context of humans and the environment. Relational thinking may seem intuitive because it recognizes the world's inherent interconnectedness. However, the question of how to operationalize
Rachelle K. Gould +6 more
wiley +1 more source
Abstract Snake envenomation remains a critical global public health challenge. In Brazil, the genus Bothrops is responsible for most accidents, typically resulting in coagulopathy, hemorrhage, and renal failure. Despite its clinical prevalence, the molecular mechanisms driving plasma protein disturbances remain poorly understood.
Bianca C. S. C. de Barros +6 more
wiley +1 more source
ABSTRACT Introduction Current recycling measures for closing the phosphorus (P) cycle are limited by the lower fertiliser use efficiencies of recycled products. Increasing P use efficiency (PUE) through maize genotype selection and management may offer a sustainable solution, but the potential of variety choice and its interaction with placed ...
Michelle Natalie Herrmann +3 more
wiley +1 more source
Theranostic π Electron‐Stabilized Polymeric Micelles for PET Imaging‐Guided Drug Delivery to Tumors
Cancer nanomedicine efficacy is limited by heterogeneous nanoparticle accumulation in tumors. Nuclear imaging offers non‐invasive, patient‐ and lesion‐specific visualization and quantification of nanoparticle uptake. We present a positron emission tomography (PET)‐imageable micelle platform for direct quantification of nanoparticle accumulation and ...
Alec Wang +21 more
wiley +1 more source
Too Little, Too Weak? Paid Parental Leaves in Philippine Collective Bargaining Agreements
ABSTRACT When statutory work–family entitlements are deemed insufficient, workers often rely on collective bargaining to secure better terms. However, the extent to which unions can deliver higher than statutory benefits remains underexplored, especially in developing countries with decentralized bargaining systems and low union salience. Bridging this
Vincent Jerald Ramos
wiley +1 more source
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah +7 more
wiley +1 more source
The influence of fertilization on chemical composition of 'Grk bijeli' [PDF]
Grk bijeli je sorta vinove loze usko vezana za mjesto Lumbarda na otoku Korčuli. Ime je dobila po gorkastom okusu, odnosno po riječi 'gark' koja na staroslavenskom ima značenje 'gorak'.
Petković, Fran Zvonimir
core
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
ABSTRACT The present study aimed to model university students' behavioral intention in Kazakhstan to use ChatGPT for academic purposes, based on the extended technology acceptance model (TAM), and to examine correlations among variables expected to influence behavioral intention. A quantitative research method was employed in this study, which involved
Lazura Kazykhankyzy +4 more
wiley +1 more source

