Results 41 to 50 of about 4,151 (197)

3D Liquid Crystal Framework Enclosing Dual Compartments

open access: yesAngewandte Chemie, EarlyView.
A new type of liquid crystal phase is reported, having the conjugated rod‐like molecular cores form a 3D framework of elongated octahedral cages filled alternatively with alkyl and fluoroalkyl pendant chains. The cages are held together by flexible H‐bonding hinges, making them adaptable to thermal expansion and stable in a wide temperature range.
Yang‐yang Zhao   +7 more
wiley   +2 more sources

GPCR Signaling Regulation: The Role of GRKs and Arrestins [PDF]

open access: yesFrontiers in Pharmacology, 2019
Every animal species expresses hundreds of different G protein-coupled receptors (GPCRs) that respond to a wide variety of external stimuli. GPCRs-driven signaling pathways are involved in pretty much every physiological function and in many pathologies. Therefore, GPCRs are targeted by about a third of clinically used drugs.
Vsevolod V. Gurevich   +1 more
openaire   +3 more sources

Infrarakentamisen betonitöiden tyypillisten laatupoikkeamien ehkäiseminen [PDF]

open access: yes, 2020
Laatu ja laadunvarmistus ovat tänä päivänä yhä tärkeämpiä osatekijöitä rakentamisessa. Laadun tulisi täyttää odotukset, sekä määräykset, joita hankkeen eri osapuolet työlle osoittavat.
Vartiainen, Joel
core  

Perhitungan Tapak Karbon Pada Aspek Pengelolaan Sampah Di TPST 3R Mulyoagung Bersatu Sebagai Upaya Pengurangan Emisi Gas Rumah Kaca

open access: yesJurnal Sumberdaya Alam dan Lingkungan, 2022
ABSTRAK Meningkatnya jumlah penduduk, pertumbuhan ekonomi dan adanya perubahan pola konsumsi masyarakat berbanding lurus dengan jumlah, jenis dan karakteristik sampah.
Bambang Suharto   +2 more
doaj   +1 more source

The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2007
G protein-coupled receptor kinases (GRKs) and arrestins are key participants in the canonical pathways leading to phosphorylation-dependent GPCR desensitization, endocytosis, intracellular trafficking and resensitization as well as in the modulation of important intracellular signaling cascades by GPCR.
Ribas, Catalina   +7 more
openaire   +2 more sources

Adding another GRK to the fire of heart failure

open access: yesEuropean Heart Journal, 2020
Abstract
Roy, Rajika, Koch, Walter J
openaire   +2 more sources

flp-1 significantly suppresses the exploration defect of grk-2.

open access: yes, 2023
(A) grk-2(gk268) mutant animals have an exploration defect and flp-1(ok2811) significantly suppresses this defect. Shown is the number of squares (out of 50) single animals covered in ~20 h.
David M. Raizen (8742261)   +6 more
core   +1 more source

Peningkatan Kualitas Penghitungan Emisi Gas Rumah Kaca dari Sektor Pengelolaan Sampah dengan Metode IPCC 2006 (Studi Kasus: Kota Cilacap)

open access: yesJurnal Ilmu Lingkungan, 2020
Gas rumah kaca (GRK) berpotensi diemisikan dari berbagai tahapan dalam pengelolaan sampah, termasuk dari tahap penanganan sampah di sumber, pengangkutan dan penimbunan sampah di tempat pemrosesan akhir (TPA).
Mochammad Chaerul   +2 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Multi‐Stimuli Responsive Angstrom‐Scale Two‐Dimensional Channels of Natural Layered Materials

open access: yesAdvanced Materials, EarlyView.
Å‐scale ion channels naturally formed within the interlayers of vermiculite clay enable ionic current modulation in response to mechanical, chemical, and electrical stimuli. Coupled pressure and electric fields induce reversible streaming current (Istream) polarity inversion, which is explained by a modified surface charge regulation model.
Raj Kumar Gogoi   +5 more
wiley   +1 more source

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