Results 21 to 30 of about 35,270 (239)
G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans. [PDF]
, 2017 G protein-coupled receptors (GPCRs) regulate many animal behaviors. GPCR signaling is mediated by agonist-promoted interactions of GPCRs with heterotrimeric G proteins, GPCR kinases (GRKs), and arrestins.
Aryal, Dipendra K. +5 more
core +2 more sources
Frontiers in Immunology, 2022 G-protein coupled receptor kinases (GRKs) participate in the regulation of chemokine receptors by mediating receptor desensitization. They can be recruited to agonist-activated G-protein coupled receptors (GPCRs) and phosphorylate their intracellular ...
Katharina M. Glaser +4 more
doaj +1 more source
GRK 26: Herodotus and Thucydides [PDF]
, 2017 Syllabus and bibliography for an advanced Greek seminar taught at Dartmouth in Winter ...
Michael Lurie
core +1 more source
The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs [PDF]
Journal of Biological Chemistry, 2006 We describe the 2.6-A crystal structure of human G protein-coupled receptor kinase (GRK)-6, a key regulator of dopaminergic signaling and lymphocyte chemotaxis. GRK6 is a member of the GRK4 subfamily of GRKs, which is represented in most, if not all, metazoans.
David T, Lodowski +3 more
openaire +2 more sources
GRKs as Key Modulators of Opioid Receptor Function [PDF]
Cells, 2020 Understanding the link between agonist-induced phosphorylation of the mu-opioid receptor (MOR) and the associated physiological effects is critical for the development of novel analgesic drugs and is particularly important for understanding the mechanisms responsible for opioid-induced tolerance and addiction.
Laura Lemel +2 more
openaire +3 more sources
Rational Cohomology Algebra of Mapping Spaces between Complex Grassmannians
International Journal of Mathematics and Mathematical Sciences, 2020 We consider the complex Grassmannian Grk,n of k-dimensional subspaces of ℂn. There is a natural inclusion in,r:Grk,n↪Grk,n+r. Here, we use Sullivan models to compute the rational cohomology algebra of the component of the inclusion in,r in the space of ...
Paul Antony Otieno +2 more
doaj +1 more source
GRKs and arrestins: regulators of migration and inflammation [PDF]
Journal of Leukocyte Biology, 2006 AbstractIn the immune system, signaling by G protein-coupled receptors (GPCRs) is crucial for the activity of multiple mediators, including chemokines, leukotrienes, and neurotransmitters. GPCR kinases (GRKs) and arrestins control GPCR signaling by mediating desensitization and thus, regulating further signal propagation through G proteins.
Anne, Vroon +2 more
openaire +2 more sources
Moment curves and cyclic symmetry for positive Grassmannians [PDF]
, 2019 We show that for each k and n, the cyclic shift map on the complex Grassmannian Gr(k,n) has exactly $\binom{n}{k}$ fixed points. There is a unique totally nonnegative fixed point, given by taking n equally spaced points on the trigonometric moment curve (
Karp, Steven N.
core +1 more source
Relative Gottlieb Groups of Embeddings between Complex Grassmannians
International Journal of Mathematics and Mathematical Sciences, 2021 Let Grk,n be the complex Grassmann manifold of k-linear subspaces in ℂn. We compute rational relative Gottlieb groups of the embedding i:Grk,n⟶Grk,n+r and show that the G-sequence is exact if r≥kn−k.
J. B. Gatsinzi
doaj +1 more source
Gallai-Ramsey Numbers for Rainbow S3+S_3^ + and Monochromatic Paths
Discussiones Mathematicae Graph Theory, 2022 Motivated by Ramsey theory and other rainbow-coloring-related problems, we consider edge-colorings of complete graphs without rainbow copy of some fixed subgraphs.
Li Xihe, Wang Ligong
doaj +1 more source