Results 81 to 90 of about 23,956 (223)

Analysis of GroE-assisted Folding under Nonpermissive Conditions [PDF]

Journal of Biological Chemistry, 1999
The molecular chaperones GroEL and GroES facilitate protein folding in an ATP-dependent manner under conditions where no spontaneous folding occurs. It has remained unknown whether GroE achieves this by a passive sequestration of protein inside the GroE cavity or by changing the folding pathway of a protein.
H, Grallert, J, Buchner
openaire   +2 more sources

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 515-528, February 2026.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

Apartheid Baltimore Style: The Residential Segregation Ordinances of 1910-1913 [PDF]

, 1983
On May 15, 1911, Baltimore Mayor J. Barry Mahool signed into law an ordinance for “preserving the peace, preventing conflict and ill feeling between the white and colored races in Baltimore City.” This ordinance provided for the use of separate blocks by
Power, Garrett
core   +1 more source

A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection [PDF]

, 2016
Background: Polymicrobial infections represent a great challenge for the clarification of disease etiology and the development of comprehensive diagnostic or therapeutic tools, particularly for fastidious and difficult-to-cultivate bacteria. Using bovine
Boye, Mette, Jensen, Tim K., Klitgaard, Kirstine, Marcatili, Paolo, Nielsen, Martin W., Nielsen, Morten, Schafer Nielsen, Claus, Sicheritz Ponten, Thomas   +7 more
core   +7 more sources

SNRK3.15 Is a Crucial Component of the Sulfur Deprivation Response in Arabidopsis thaliana

Plant Direct, Volume 10, Issue 1, January 2026.
ABSTRACT Sulfate deprivation (–S) results in numerous metabolic and phenotypic alterations in plants. Kinases are often key players in transducing nutrient status signals to molecular components involved in metabolic and developmental program regulation, but despite the physiological importance of sulfur, to date, no signaling kinases have been ...
Anastasia Apodiakou, Elmien Heyneke, Saleh Alseekh, Pinnapat Pinsorn, Sabine Metzger, Stanislav Kopriva, Waltraud Schulze, Rainer Hoefgen, Sarah J. Whitcomb   +8 more
wiley   +1 more source

Immunotherapeutic Applications of Probiotics in Infectious Diseases Management: A Scoping Review

Advanced Gut &Microbiome Research, Volume 2026, Issue 1, 2026.
Probiotics are emerging as promising alternative therapies with diverse health applications, particularly in enhancing immunity and combating infectious diseases. This scoping review synthesizes evidence on the immunomodulatory and antimicrobial effects of well‐characterized strains, particularly species of Bifidobacterium and Lactobacillus. Probiotics
Samson Adedeji Adejumo, Chioma Miracle Ojiako, Pritha Das, Felix Chukwuebuka Onyia, Mavis Nkem Okafor, Ifeanyi Ferdinand Chukwuma, Jarrad Hampton-Marcell, Angus Nnamdi Oli, Jian Wu   +8 more
wiley   +1 more source

Evolvability of Chaperonin Substrate Proteins [PDF]

, 2009
Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Emanuele Raineri, Luis Serrano, Paolo Ribeca, Tobias Maier   +3 more
core   +1 more source

Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication [PDF]

, 2011
Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are visited by the protein also in the ...
Mitternacht, Simon, Berezovsky, Igor N.
core   +1 more source

Potentially Pathogenic Bacteria in Urban Indoor Air Assessed by Culture‐Dependent and Culture‐Independent Quantitative PCR Methods: A Study of Public Service Buildings in Poznań, Poland

Indoor Air, Volume 2026, Issue 1, 2026.
Potentially pathogenic airborne bacteria may pose a risk to human health, yet their prevalence in public service buildings remains largely unknown. In this study, we detected and quantified the most common potentially pathogenic bacteria in the air inside public service buildings (schools, universities, a pharmacy, and a medical clinic) in Poznań, a ...
Martyna Kryger, Anna Maćkowska, Klaudia Kortus, Ryszard Koczura, Joanna Mokracka, Parthipan Punniyakotti   +5 more
wiley   +1 more source

Increased expression and purification of soluble iron-regulatory protein 1 from Escherichia coli co-expressing chaperonins GroES and GroEL [PDF]

, 2008
Iron is an essential metal for all living organisms. However, iron homeostasis needs to be tightly controlled since iron can mediate the production of reactive oxygen species, which can damage cell components and compromise the integrity and/or cause DNA
Carvalho, Helotonio, Meneghini, Rogério
core   +2 more sources