Results 1 to 10 of about 19,683 (209)

Probiotic Characteristics of Lactic Acid Bacteria Isolated from the Intestinal Tract of Mothers and Infants in Hotan, Xinjiang

Shipin gongye ke-ji
In this study, the lactic acid bacteria from the feces of Uygur mother-infant pairs in Hotan, Xinjiang, was isolated and identified. The bacteriostatic performance of the isolates for diarrhea pathogenic bacteria was assessed, and the probiotic ...
Jianjun LI, Gulibaikeremu·AIBIBOLA, Yongqing NI, Xu LI   +3 more
doaj   +1 more source

Back to GroEL-Assisted Protein Folding: GroES Binding-Induced Displacement of Denatured Proteins from GroEL to Bulk Solution

Biomolecules, 2020
The main events in chaperone-assisted protein folding are the binding and ligand-induced release of substrate proteins. Here, we studied the location of denatured proteins previously bound to the GroEL chaperonin resulting from the action of the GroES co-
Victor Marchenkov, Andrey Gorokhovatsky, Natalia Marchenko, Tanya Ivashina, Gennady Semisotnov   +4 more
doaj   +1 more source

Mechanisms involved in the functional divergence of duplicated GroEL chaperonins in Myxococcus xanthus DK1622. [PDF]

PLoS Genetics, 2013
The gene encoding the GroEL chaperonin is duplicated in nearly 30% of bacterial genomes; and although duplicated groEL genes have been comprehensively determined to have distinct physiological functions in different species, the mechanisms involved have ...
Yan Wang, Wen-yan Zhang, Zheng Zhang, Jian Li, Zhi-feng Li, Zai-gao Tan, Tian-tian Zhang, Zhi-hong Wu, Hong Liu, Yue-zhong Li   +9 more
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Субклінічне внутрішньоутробне запалення як детермінанта екстремально ранніх передчасних пологів: інтегральний аналіз системних маркерів (власне дослідження)

Український журнал Перинатологія і педіатрія
Мета - визначити прогностичну цінність клінічних, лабораторних, ультразвукових і психоемоційних маркерів у ризику розвитку екстремально ранніх передчасних пологів (ЕРПП) на тлі внутрішньоутробного інфікування. Матеріали і методи.
O.B. Yaroshchuk, D.O. Govsieiev
doaj   +1 more source

In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution

Frontiers in Molecular Biosciences, 2023
Protein folding is often hampered by intermolecular protein aggregation, which can be prevented by a variety of chaperones in the cell. Bacterial chaperonin GroEL is a ring-shaped chaperone that forms complexes with its cochaperonin GroES, creating ...
Hideki Taguchi, Ayumi Koike-Takeshita
doaj   +1 more source

Prediction of Unwanted Crystallization of Freeze-Dried Protein Formulations Using α-Relaxation Measurements

Pharmaceutics, 2023
There is a lack of methods to predict the isothermal crystallization behavior of amorphous freeze-dried formulations stored below the glass transition temperature. This study applies isothermal microcalorimetry to predict long-term crystallization during
Sebastian Groël, Tim Menzen, Gerhard Winter   +2 more
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GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi

PLoS ONE, 2021
Rickettsioses are neglected and emerging potentially fatal febrile diseases that are caused by obligate intracellular bacteria, rickettsiae. Rickettsia (R.) typhi and R.
Jessica Rauch, Jessica Barton, Marcel Kwiatkowski, Malte Wunderlich, Pascal Steffen, Kristin Moderzynski, Stefanie Papp, Katharina Höhn, Hella Schwanke, Susanne Witt, Ulricke Richardt, Ute Mehlhoop, Hartmut Schlüter, Verena Pianka, Bernhard Fleischer, Dennis Tappe, Anke Osterloh   +16 more
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Heterologous expression of Brucella abortus GroEL heat-shock protein in Lactococcus lactis

Microbial Cell Factories, 2006
Background Brucella abortus is a facultative intracellular pathogen that mainly infects cattle and humans. Current vaccines rely on live attenuated strains of B.
Langella Philippe, Oliveira Sérgio C, Le Loir Yves, Ribeiro Luciana A, Bermúdez-Humarán Luis G, Miyoshi Anderson, Azevedo Vasco   +6 more
doaj   +1 more source

The Chaperonin GroEL: A Versatile Tool for Applied Biotechnology Platforms

Frontiers in Molecular Biosciences, 2018
The nucleotide-free chaperonin GroEL is capable of capturing transient unfolded or partially unfolded states that flicker in and out of existence due to large-scale protein dynamic vibrational modes.
Pierce T. O'Neil, Alexandra J. Machen, Benjamin C. Deatherage, Caleb Trecazzi, Alexander Tischer, Venkata R. Machha, Matthew T. Auton, Michael R. Baldwin, Tommi A. White, Tommi A. White, Mark T. Fisher   +10 more
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GroEL protein of the Leptospira spp. interacts with host proteins and induces cytokines secretion on macrophages

BMC Microbiology, 2021
Background Leptospirosis is a zoonotic disease caused by infection with spirochetes from Leptospira genus. It has been classified into at least 17 pathogenic species, with more than 250 serologic variants.
Joana Dias Ho, Luiz Eduardo Massao Takara, Denize Monaris, Aline Patrícia Gonçalves, Antonio Francisco Souza-Filho, Gisele Oliveira de Souza, Marcos Bryan Heinemann, Paulo Lee Ho, Patrícia Antonia Estima Abreu   +8 more
doaj   +1 more source