Pharmaceutics, 2023 There is a lack of methods to predict the isothermal crystallization behavior of amorphous freeze-dried formulations stored below the glass transition temperature. This study applies isothermal microcalorimetry to predict long-term crystallization during
Sebastian Groël +2 more
doaj +1 more source
An integrated native mass spectrometry and top-down proteomics method that connects sequence to structure and function of macromolecular complexes. [PDF]
, 2018 Mass spectrometry (MS) has become a crucial technique for the analysis of protein complexes. Native MS has traditionally examined protein subunit arrangements, while proteomics MS has focused on sequence identification.
Campuzano, Iain DG +4 more
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Shipin gongye ke-jiIn this study, the lactic acid bacteria from the feces of Uygur mother-infant pairs in Hotan, Xinjiang, was isolated and identified. The bacteriostatic performance of the isolates for diarrhea pathogenic bacteria was assessed, and the probiotic ...
Jianjun LI +3 more
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Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]
, 2018 Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J +6 more
core +2 more sources
Heterologous expression of
Microbial Cell Factories, 2006 Background Brucella abortus is a facultative intracellular pathogen that mainly infects cattle and humans. Current vaccines rely on live attenuated strains of B.
Langella Philippe +6 more
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Bartonella infections in fleas (Siphonaptera : Pulicidae) and lack of Bartonellae in ticks (Acari : Ixodidae) from Hungary [PDF]
, 2006 Fleas (95 Pulex irritans, 50 Ctenocephalides felis, 45 Ctenocephalides canis) and ixodid ticks (223 Ixodes ricinus, 231 Dermacentor reticulatus, 204 Haemaphysalis concinna) were collected in Hungary and tested, in assays based on PCR, for Bartonella ...
Márialigeti, Károly +4 more
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A structural model for GroEL–polypeptide recognition [PDF]
Proceedings of the National Academy of Sciences, 1997 A monomeric peptide fragment of GroEL, consisting of residues 191–376, is a mini-chaperone with a functional chaperoning activity. We have solved the crystal structure at 1.7 Å resolution of GroEL(191–376) with a 17-residue N-terminal tag. The N-terminal tag of one molecule binds in the active site of a neighboring molecule in the crystal. This appears
A M, Buckle, R, Zahn, A R, Fersht
openaire +2 more sources
Extragenic Suppression analysis of TS mutations using Sec61p [PDF]
, 2007 During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel.
Sterling Smith
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Symbiotic outcome modified by the diversification from 7 to over 700 nodule specific cysteine rich peptides [PDF]
, 2020 Legume-rhizobium symbiosis represents one of the most successfully co-evolved mutualisms. Within nodules, the bacterial cells undergo distinct metabolic and morphological changes and differentiate into nitrogen-fixing bacteroids.
Achom, Mingkee +4 more
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Upscaling the surveillance of tick-borne pathogens in the French Caribbean Islands [PDF]
, 2020 Despite the high burden of vector-borne disease in (sub)tropical areas, few information are available regarding the diversity of tick and tick-borne pathogens circulating in the Caribbean.
Albina, Emmanuel +9 more
core +3 more sources