Results 21 to 30 of about 19,683 (209)
Gut Microbes, 2021 Gut microbiota and the immune system are in constant exchange shaping both host immunity and microbial communities. Here, improper immune regulation can cause inflammatory bowel disease (IBD) and colitis. Antibody therapies blocking signaling through the
Verena Friedrich +11 more
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Український журнал Здоров'я жінки, 2022 Жiнки клiмактеричнoгo вiку становлять 10% популяції Землі, і наразі проблема патологічного клімактерію залишається актуальною. Причиною розвитку клімактерію вважається дефіцит естрогенів, тому використання замісної терапії є патогенетично обґрунтованим ...
I.V. Sokol, D.O. Govsieiev
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GroEL and the maintenance of bacterial endosymbiosis [PDF]
Trends in Genetics, 2004 Many eukaryotic organisms have symbiotic associations with obligate intracellular bacteria. The clonal transmission of endosymbionts between host generations should lead to the irreversible fixation of slightly deleterious mutations in their non-recombinant genome by genetic drift.
Fares, Mario Ali +2 more
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GroEL‐Mediated protein folding [PDF]
Protein Science, 1997 Abstract Architecture of GroEL and GroES and the reaction pathway Architecture of the chaperonins Reaction pathway of GroEL‐GroES‐mediated folding Polypeptide binding A parallel network of chaperones binding polypeptides in vivo Polypeptide binding in vitro Role of hydrophobicity in recognition Homologous proteins with differing recognition ...
W A, Fenton, A L, Horwich
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A structural model for the GroEL chaperonin [PDF]
FEMS Microbiology Letters, 1993 Individual particle analysis of end views from negatively stained specimens of purified GroEL from Escherichia coli showed the presence of two different particle populations, those with a six-fold symmetry and those with a seven-fold symmetry, when studied at pH 7.7 and 5.0.
S, Marco +5 more
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Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats. [PDF]
PLoS ONE, 2014 Porphyromonas gingivalis is a major periodontal pathogen that contains a variety of virulence factors. The antibody titer to P. gingivalis GroEL, a homologue of HSP60, is significantly higher in periodontitis patients than in healthy control subjects ...
Feng-Yen Lin +9 more
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Journal of the Formosan Medical Association, 2021 Background/Purpose: Porphyromonas gingivalis is an oral pathogen associated with periodontal diseases. P. gingivalis GroEL protein is a stimulator of inflammatory cytokines in macrophages. This study inspected effects of P.
Hsiu-Hui Lin +5 more
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In vivo activities of GroEL minichaperones
, 1998 Fragments encompassing the apical domain of GroEL, called minichaperones, facilitate the refolding of several proteins in vitro without requiring GroES, ATP, or the cage-like structure of multimeric GroEL.
Hill, F +3 more
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Foods, 2023 The molecular chaperone GroEL of C. sakazakii, a highly conserved protein encoded by the gene grol, has the basic function of responding to heat shock, thus enhancing the bacterium’s adaptation to dry and high-temperature environments, which poses a ...
Dongdong Zhu +9 more
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Dynamics of allosteric transitions in GroEL [PDF]
Proceedings of the National Academy of Sciences, 2006 The chaperonin GroEL-GroES, a machine that helps proteins to fold, cycles through a number of allosteric states, the T state, with high affinity for substrate proteins, the ATP-bound R state, and the R ″ (
Hyeon, Changbong +2 more
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