Results 71 to 80 of about 80,126 (312)

Somatosensory Outcomes Following Re-Surgery in Persistent Severe Pain After Groin Hernia Repair: A Prospective Observational Study

Journal of Pain Research, 2023
Elisabeth Kjær Jensen,1,* Thomas K Ringsted,1,* Joakim M Bischoff,1 Morten A Petersen,2 Kirsten Møller,3,4 Henrik Kehlet,5 Mads U Werner1,6 1Department of Anaesthesia, Pain and Respiratory Support, Copenhagen University Hospital-Rigshospitalet ...
Jensen EK, Ringsted TK, Bischoff JM, Petersen MA, Møller K, Kehlet H, Werner MU   +6 more
doaj  

4 Pre-season hip/groin strength and ratings of health are associated with prospective injury in professional footballers

, 2019
Background Hip and groin injuries are a significant cause of time lost from training and competition in elite football. Purpose To explore the association between hip/groin injury in professional footballers and pre-season assessment of 1) hip adductor ...
Pizzari, Tania, Ryan Timmins, Williams, Morgan, Matthew Bourne, Tania Pizzari, Bourne, Matthew, Morgan Williams, Timmins, Ryan   +7 more
core   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Unusual groin swellings [PDF]

Postgraduate Medical Journal, 1984
It is important to remember that a swelling in the groin may be part of a generalized disease or may arise from a structure peculiar to the region. It is therefore pertinent in patients presenting with swellings in the groin always to examine the groin in conjunction with the rest of the body and not in isolation.
P A, Farrands, I, Taylor
openaire   +2 more sources

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Inguinal-related groin pain in athletes: a pathological potpourri

BMJ Open Sport & Exercise Medicine, 2022
Adam Weir, Zarko Vuckovic, Andreas Serner, Willem M P Heijboer   +3 more
doaj   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Longstanding Adduction-related Groin Pain in Athletes [PDF]

, 2010
Although participation in sports is considered important by the Dutch government, it does increase the risk for musculoskeletal injury. Every year, about 3,500,000 sports injuries occur in the Netherlands (Schmikli et al., 2004). In this thesis, emphasis
Jansen, JACG, Jansen, J.A.C.G. (Jaap)
core   +1 more source

Preseason Hip/Groin Strength and HAGOS Scores Are Associated With Subsequent Injury in Professional Male Soccer Players.

, 2019
STUDY DESIGN: Prospective cohort. BACKGROUND: Hip and groin injuries are a significant cause of time lost from training and competition in elite soccer.
Pizzari, Tania, Williams, Kate L, Bourne, Matthew N, Timmins, Ryan G, Jackson, Jeremy, Williams, Morgan   +5 more
core   +1 more source