Results 291 to 300 of about 1,140,631 (389)

Scalable Lignin Monomer Production Via Machine Learning‐Guided Reductive Catalytic Fractionation of Lignocellulose

open access: yesAdvanced Science, EarlyView.
This study pioneers an integrated machine learning framework combining large‐scale data modeling, experimental validation, and impact analysis to optimize reductive catalytic fractionation for scalable, sustainable lignin monomer production. Abstract Efficient valorization of lignocellulosic biomass into high‐value lignin monomers is a cornerstone of ...
Meysam Madadi   +7 more
wiley   +1 more source

Enzalutamide‐Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone‐Sensitive Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Expanding enzalutamide (ENZ) use in hormone‐sensitive prostate cancer (HSPC) faces resistance. Single‐cell profiling identifies therapy‐resistant STEAP4+ myofibroblastic cancer‐associated fibroblast (SETAP4+ myoCAF). These myoCAFs drive resistance via TFE3‐mediated autophagy and PCYT1A‐led phosphatidylcholine overproduction, creating a phospholipid ...
Wenhao Wang   +14 more
wiley   +1 more source

One‐Pot Encapsulation of Enzymes in a Calcium Carboxylate Metal‐Organic Framework for Improved Buffer Stability

open access: yesAdvanced Science, EarlyView.
A biocompatible, room‐temperature synthesis of Ca2⁺–4,5‐imidazoledicarboxylate MOFs enables in situ encapsulation of diverse enzymes with enhanced stability in phosphate buffer. A machine learning workflow integrating Latin hypercube sampling efficiently navigates the synthesis space, optimizing encapsulation efficiency, retained enzymatic activity ...
Ying Shu, Weibin Liang, Jun Huang
wiley   +1 more source

First reported case of pediatric radiation treatment with magnetic resonance image guided radiation therapy [PDF]

open access: yes, 2019
Green, Olga L   +6 more
core   +1 more source

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

open access: yesAdvanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang   +10 more
wiley   +1 more source

Gross Anatomy

open access: yesThe Iowa Review, 2009
openaire   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay   +3 more
wiley   +1 more source

A Modern Roman‐Inspired Concrete with Daytime Radiative Cooling Capacity

open access: yesAdvanced Science, EarlyView.
Coolcrete, inspired by ancient Roman concrete, is a new cementitious material with photonic properties enabling passive daytime radiative cooling. Made from quicklime and zeolites, it reduces cooling energy demand, lowers CO2 emissions, and may eliminate urban heat islands.
Jorge S. Dolado   +11 more
wiley   +1 more source

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