Results 51 to 60 of about 4,200,663 (304)

Identification of a general light use efficiency model for gross primary production [PDF]

Biogeosciences, 2011
Non-stationary and non-linear dynamic time series analysis tools are applied to multi-annual eddy covariance and micrometeorological data from 44 FLUXNET sites to derive a light use efficiency model for gross primary production on a daily basis.
J. E. Horn, K. Schulz
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Space Efficiency in Finnish Mid-Rise Timber Apartment Buildings

Buildings, 2023
As in many other building types, space efficiency in mid-rise timber apartment buildings is one of the critical design parameters to make a project feasible.
Antti Tuure, Hüseyin Emre Ilgın
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Steep uphill cycling using repeated transitions between seated and standing positions results in a lower blood-lactate concentration than continuous use of either seated or standing position

Frontiers in Sports and Active Living
This study investigated whether repeated transitions between seated and standing positions has a different physiological response compared to continuous use of either seated position or standing position during steep uphill cycling among elite cyclists ...
Magnus Carlsson, Oliver Lindblom, Tomas Carlsson   +2 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

CONTRIBUTION OF SUBSIDIES TO THE LEVEL OF INCOME OF SMALL FARMS IN BULGARIA [PDF]

Journal of Bio-Based Marketing, 2020
The article examines the relationship between subsidies paid and the profitability achieved on small agricultural holdings in Bulgaria. The regression analysis examines the relationship between subsidies as factorial values ​​and indicators – gross ...
Nikolaj Stefanov
doaj  

WUE and CO₂ Estimations by Eddy Covariance and Remote Sensing in Different Tropical Biomes

Remote Sensing, 2022
The analysis of gross primary production (GPP) is crucial to better understand CO2 exchanges between terrestrial ecosystems and the atmosphere, while the quantification of water-use efficiency (WUE) allows for the estimation of the compensation between ...
Gabriel B. Costa, Cláudio M. Santos e Silva, Keila R. Mendes, José G. M. dos Santos, Theomar T. A. T. Neves, Alex S. Silva, Thiago R. Rodrigues, Jonh B. Silva, Higo J. Dalmagro, Pedro R. Mutti, Hildo G. G. C. Nunes, Lucas V. Peres, Raoni A. S. Santana, Losany B. Viana, Gabriele V. Almeida, Bergson G. Bezerra, Thiago V. Marques, Rosaria R. Ferreira, Cristiano P. Oliveira, Weber A. Gonçalves, Suany Campos, Maria U. G. Andrade   +21 more
doaj   +1 more source