Results 41 to 50 of about 4,200,663 (304)

Physiological Comparisons of Elite Male Visma Ski Classics and National Level Cross-Country Skiers During Uphill Treadmill Roller Skiing

Frontiers in Physiology, 2018
Longer distance cross-country ski (14–220 km) races such as the Visma Ski Classics (VSC) has recently gained attention in addition to the traditional Olympic distances (5–50 km) associated with cross-country (XC) skiing.
Edvard H. Sagelv, Tina P. Engseth, Sigurd Pedersen, Svein A. Pettersen, Gunnar Mathisen, Kim A. Heitmann, Boye Welde, Tor O. Thomassen, Thomas L. Stöggl   +8 more
doaj   +1 more source

Analysis of influence of steam-turbine cycle basic parameters on the efficiency of triple combined-cycle plants

Известия Томского политехнического университета: Инжиниринг георесурсов, 2009
The profile of the advanced triple cycle steam-gas plant has been selected. The authors have developed the mathematical model for calculating the indicators of triple cycle steam-gas plant.
N. N. Galashov, S. A. Tsibulsky
doaj   +2 more sources

Output volatility and efficiency gains: evidence from Latin American gross value added

Journal of Applied Economics, 2021
Based on gross value added (GVA) shares of economic activities from 1990 to 2014, the paper shows that convex growth-instability frontiers exist for 19 Latin American countries. Numerical simulations show that in 2011, Latin America's industry portfolios
Kurt A. Hafner
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Experimental Investigation of a 300 kW Organic Rankine Cycle Unit with Radial Turbine for Low-Grade Waste Heat Recovery

Entropy, 2019
The performance of a 300 kW organic Rankine cycle (ORC) prototype was experimentally investigated for low-grade waste heat recovery in industry. The prototype employed a specially developed single-stage radial turbine that was integrated with a semi ...
Ruijie Wang, Guohua Kuang, Lei Zhu, Shucheng Wang, Jingquan Zhao   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effects of familiarization on reliability of muscle-activation and gross efficiency in adolescents and adults [PDF]

Cogent Medicine, 2016
We investigated the effects of familiarization on the reliability of gross efficiency (GE) and lower-limb electromyography (EMG-rms) of adults and adolescents. We also evaluated the relationship between inter-test differences in GE and EMG-rms. Nine adult and nine adolescent cyclists performed three 10-min cycling tests at 50% of peak power output ...
Mark Waldron, Jamie Highton, Adrian Gray
openaire   +4 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Determining the Efficiency and Inefficiency Intervals of Crop Production in Iran [PDF]

پژوهشهای اقتصادی, 2020
In this study, using the classic and developed models of data envelopment analysis, the frontiers of efficiency and inefficiency were determined for 29 irrigated crops and the relative position of products was determined in terms of gross income and ...
ali shahnavazi
doaj