Results 191 to 200 of about 125,919 (301)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Organic and Conventional Farming: a Comparison Analysis through the Italian FADN

open access: yes
This paper shows some results arisen from a wider research on economic and environmental sustainability of organic farming. It focuses on organic and conventional farming comparison through an investigation of Italian FADN data. In order to identify some
Madau, Fabio A., Cisilino, Federica
core   +1 more source

The efficiency paradox of discharge masking head loss in run-of-river hydropower generation. [PDF]

open access: yesSci Rep
Mugisho MJ   +7 more
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Carbohydrate ingestion improves gross cycling efficiency and subsequent time-trial performance

open access: yes
Introduction: Whilst many research studies monitor and report improvements in cycling efficiency (Coyle et al., 2005; Hopker et al., 2009), none state whether nutritional intake was controlled or recorded across the period of assessment.
Coleman, Damian A   +3 more
core  

Effect of plant bio-stimulants on productivity, bio-energy efficiency and profitability of a berseem-pearl millet cropping system. [PDF]

open access: yesFront Microbiol
Reddy MB   +11 more
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

LEAST COST EFFICIENCY OF AGRICULTURAL PROGRAMS: AN EMPIRICAL INVESTIGATION

open access: yes
The study evaluates the efficiency of government intervention using a vertical structured model including imperfectly competitive agricultural input markets, the bread grains market, and the imperfectly competitive food industry.
Salhofer, Klaus   +2 more
core   +1 more source

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