Results 41 to 50 of about 1,490,342 (299)

Longitudinal Association Between Gross Motor Capacity and Neuromusculoskeletal Function in Children and Youth With Cerebral Palsy [PDF]

open access: yes, 2016
Objective To examine associations over longitudinal measurements between neuromusculoskeletal function and gross motor capacity in children and youth with cerebral palsy (CP). Design A prospective cohort study.
Reinders-Messelink, H. A.   +30 more
core   +2 more sources

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Gross motor development, physical activity and anthropometry of Grade 1’s in a South African school

open access: yesSouth African Journal of Childhood Education
Background: Gross motor difficulties can limit physical activity (PA) participation, contributing to unhealthy body composition. Aim: This study profiled Grade 1 learners’ gross motor development, PA and anthropometry and explored relationships between ...
Monique de Milander   +3 more
doaj   +1 more source

Association between executive functions and gross motor skills in overweight/obese and eutrophic preschoolers: cross-sectional study

open access: yesBMC Pediatrics, 2022
Background Preschool age (3–5 years old) is a crucial period for children to acquire gross motor skills and develop executive functions (EFs). However, the association between the qualitative gross motor skills and EFs remains unknown in preschoolers ...
Amanda Cristina Fernandes   +15 more
doaj   +1 more source

Fine and gross motor ability in males with ADHD [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2003
In the this study, both fine and gross motor ability of males with attention‐deficit‐hyperactivity disorder (ADHD) were compared with a group of control children. Three groups of males with the following ADHD subtypes: predominantly inattentive (ADHD‐PI; n=50), hyperactive/impulsive (ADHD‐HI; n=16), or combined (ADHD‐C; n=38) were compared with 39 ...
Pitcher, T., Piek, Jan, Hay, David
openaire   +3 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Review of four tests of gross motor development [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2001
In 1937, Orton described children with motor coordination difficulties as ‘clumsy’, a term still used today. Other terms used to describe these difficulties include developmental dyspraxia, awkwardness, motor learning problems, and most recently, developmental coordination disorder (DCD).
L, Wiart, J, Darrah
openaire   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

The effect of early perceptual-motor enrichment on later development of gross motor processes in infants

open access: yesمجله پژوهش در علوم توانبخشی, 2011
Introduction: The purpose of this study was to investigate the effect of early perceptual-motor enrichment on later development of gross motor processes in infants.
Alireza Farsi   +3 more
doaj   +1 more source

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