Results 31 to 40 of about 3,683 (215)

Motor and cognitive functioning in children treated for idiopathic clubfoot at the age of 3 years

BMC Pediatrics, 2019
Background Several studies have investigated motor and cognitive skills in infants as well as gross motor abilities in schoolchildren treated for congenital idiopathic clubfoot, mostly indicating specific impairments in those children. However, until now,
Julia Dillmann, Gudrun Schwarzer, Christian-Dominik Peterlein   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of Balance Training with Swiss Ball on Gross Motor Skill of Children with Attention Deficit – Hyperactivity Disorder [PDF]

رشد و یادگیری حرکتی ورزشی, 2015
Fundamental motor skills are key components of motor development and are divided into two main sub groups including fine and gross motor skills. The main purpose of the present study was to determine the effect of balance training with Swiss ball (BTWSB)
Farideh Shafati, Ahmadreza Movahedi, Hamid Salehi   +2 more
doaj   +1 more source

Fine and gross motor ability in males with ADHD [PDF]

Developmental Medicine & Child Neurology, 2003
In the this study, both fine and gross motor ability of males with attention‐deficit‐hyperactivity disorder (ADHD) were compared with a group of control children. Three groups of males with the following ADHD subtypes: predominantly inattentive (ADHD‐PI; n=50), hyperactive/impulsive (ADHD‐HI; n=16), or combined (ADHD‐C; n=38) were compared with 39 ...
Pitcher, T., Piek, Jan, Hay, David
openaire   +3 more sources

Gross motor development in children with epidermolysis bullosa

Child: Care, Health and Development, 2023
AbstractBackgroundEpidermolysis bullosa (EB) is a group of rare, congenital skin disorders, characterized by skin fragility and formation of blisters. The gross motor outcomes of children with EB are not known.ObjectivesThe primary objective of the study was to measure the proportion of gross motor delay in children with EB.
Andrew Gorrie, Rebecca Saad, Lydia Garside, Claire Bailie, Orli Wargon   +4 more
openaire   +2 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Gross motor development, physical activity and anthropometry of Grade 1’s in a South African school

South African Journal of Childhood Education
Background: Gross motor difficulties can limit physical activity (PA) participation, contributing to unhealthy body composition. Aim: This study profiled Grade 1 learners’ gross motor development, PA and anthropometry and explored relationships between ...
Monique de Milander, Elna van der Merwe, Bianca Barnard, Robynne Verster   +3 more
doaj   +1 more source

TEACHER’S EXPERIENCES OF TEACHING GROSS MOTOR SKILL FOR CHILDREN WITH OBESITY: A PHENOMENOLOGICAL STUDY

Jurnal Ilmiah Didaktika: Media Ilmiah Pendidikan dan Pengajaran, 2020
Improving gross motor skill in early childhood education is very important. However, few qualitative studies have investigated teachers’ experience of teaching gross motor skill with obese children.
Muchammad Arif Muchlisin
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source