Results 51 to 60 of about 1,840,889 (282)

Gross Motor Skills in Children With Idiopathic Clubfoot and the Association Between Gross Motor Skills, Foot Involvement, Gait, and Foot Motion

Journal of Pediatric Orthopaedics, 2019
Background: Little is known regarding gross motor skills (GMS) in children with idiopathic clubfoot (IC). This study describes GMS, specifically foot involvement and asymmetries, and analyses the association between GMS, gait, and foot status in children with IC.
Elin, Lööf, Hanneke, Andriesse, Marie, André, Stephanie, Böhm, Maura D, Iversen, Eva W, Broström   +5 more
openaire   +3 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Strengthening Gross Motor Skill of Children with Intellectual Disability Using Circuit Training

Jurnal Penelitian dan Pengembangan Pendidikan Luar Biasa, 2018
The aim of this research is to identify the effect of Circuit Training towards gross motor skills on children with moderate intellectual disability in SDLBN Kedungkandang Malang. The research implements Single Subject Research design type A-B-A.
Desi Chuluqi Fitri, Sopingi Sopingi, Sihkabuden Sihkabuden   +2 more
doaj   +1 more source

Motor Skill Development in Italian Pre-School Children Induced by Structured Activities in a Specific Playground. [PDF]

PLoS ONE, 2016
This study examined the effects and specificity of structured and unstructured activities played at the playground Primo Sport 0246 in Northern Italy on motor skill competence in five years old children.
Patrizia Tortella, Monika Haga, Håvard Loras, Hermundur Sigmundsson, Guido Fumagalli   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Pedagogical feedback in the motor skill domain for computer-based sports training

, 2010
With the rapid development of Computer-based Sport Training (CBST), feedback plays an important role in both coaching and learning. A good CBST system includes not only good training strategies but also effective feedback design.
P Iskandar, Yulita Hanum
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Association between idiopathic toe walking and gross motor skill development in early childhood

Liaquat Medical Research Journal
The objective of this cross-sectional study was to establish the association between idiopathic toe walking and gross motor skill acquisition among children aged 4 to 10 years.
Asharib Rathore, Maryam Shabbir, Rabia Majeed, Aqsa Majeed, Aqsa Abid, Qurat ul Ain, Hafiza Amna Akram, Sadaf Anjum   +7 more
doaj   +1 more source

Peningkatan Keterampilam Motorik Kasar Melalui Kegiatan Tari Binatang pada Anak Kelompok B TK PGRI I Langkap

Jurnal PG-PAUD Trunojoyo, 2016
The purpose of this research was to increasing gross motor skilsl of child through animal dance in group B TK PGRI 1 Langkap. This research was done because there are problems in gross motor skilsl in child in group B TK PGRI 1 Langkap.
Denok Dwi Anggraini, St Aini Farah Dhiba, Asmi Ittari   +2 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source