Results 41 to 50 of about 44,451 (255)

The Influence of the Number of Employed Population, Gross Regional Domestic Product, and Investment on Regional Original Income in Regencies/Cities of Central Java Province

Indonesian Interdisciplinary Journal of Sharia Economics
Regional original income is one of the benchmarks in measuring the independence of a region. The achievement of regional original income can be influenced by external factors.
Ma’ruf Affandi, Agus Budi Santosa
doaj   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Modeling an aggregated indicator of regional economic security level through the prism of key determinants

Вестник университета
The interrelationships of economic, demographic, and social factors determining regional economic security have been studied using the Krasnodar Region case. The study covers the period 2012-2022 and includes an analysis of 12 significant indicators such
T. V. Vaskevich, T. I. Litvinova, J. O. Ryabchikova   +2 more
doaj   +1 more source

THE ROLE OF AGRICULTURAL SECTOR IN BANTUL REGION DEVELOPMENT

Caraka Tani: Journal of Sustainable Agriculture, 2017
This research is aimed to find out the ability of agricultural sector in supporting government’s development and the role of agricultural sector in the development of Bantul region. This research uses descriptive method.
Vini Arumsari, Wulandari Dwi Etika Rini
doaj   +1 more source

Assessment of the Impact of Investments in Fixed Capital on the Economic Growth of the Northern Regions of the Russian Federation

Статистика и экономика, 2023
The purpose of the study. Despite the fact that a significant amount of research work has been accumulated on northern and Arctic topics, there is a lack of relevant research on the relationship between investments in fixed assets and economic growth for
A. Ts. Dolgunova
doaj   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Regional Government Revenue Forecasting: Risk Factors of Investment Financing

Risks, 2021
Accurate revenue prediction is a key factor for the reliable determination of the investment part of entire regional and local budgets, particularly during economic downturns and fiscal uncertainty. An unexpected decline in revenue requires the reduction
Barbara Batóg, Jacek Batóg
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source