Results 121 to 130 of about 8,361,399 (394)
One State, Two States, Whatever Everybody Wants [PDF]
, 2017 Speaker Miri Eisin lectured about the current political climate of Israel and Palestine.College of ...
Boston University Howard Thurman Center for Common Ground
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Caring for victims of torture: Lecture & reception with Professor Michael Grodin [PDF]
, 2008 A discussion with Professor Michael Grodin on caring for victims of ...
Boston University Howard Thurman Center for Common Ground
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Tea Time: de-stress before finals [PDF]
, 2018 Weekly Tea Time program featuring the topic "De-Stress before finals"Boston University Howard Thurman Center for Common ...
Boston University Howard Thurman Center for Common Ground
core
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Euthanasia: above ground, below ground [PDF]
Journal of Medical Ethics, 2004 The key to the euthanasia debate lies in how best to regulate what doctors do. Opponents of euthanasia frequently warn of the possible negative consequences of legalising physician assisted suicide and active euthanasia (PAS/AE) while ignoring the covert practice of PAS/AE by doctors and other health professionals.
openaire +3 more sources
Building a better tomorrow--student organization trainings [PDF]
, 2005 The Center hosted 3 different training programs for student leadership training and professional ...
Boston University Howard Thurman Center for Common Ground
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Strategies for Sustainable Rooting in Landscape: Arrangements between Architecture and the Ground
BuildingsContemporary environmental awareness requires new architectural practices to reformulate the relationship between buildings and the ground. Among these, the way in which buildings land on the site emerges as a key architectural condition that must be ...
David Casino Rubio +2 more
doaj +1 more source