Results 81 to 90 of about 8,737,298 (395)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
An afternoon with Stan Salett [PDF]
The center host an afternoon with Stan Salett for conversation and questions.New England Educational Opportunity ...
Boston University Howard Thurman Center for Common Ground
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Calculation of reliability of foundation beds according to the strength criterion with limited information about the load [PDF]
This article deals with a safety problem of upkeep of buildings and structures, specifically soil reliability according to the strength criterion with absolutely limited information about pressure by building foundation on the ground.For solving the ...
V.S. Utkin, E.A. Shepelina
doaj
The Howard Thurman Center host a Russian culture night and feature traditional foods and ...
Boston University Howard Thurman Center for Common Ground
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
JUSTIFICATION OF LOADS ON CRAWLER MOVERS-MOVING MACHINES [PDF]
The issues concerning determination of loading on excavator track drive equipment are considered.
Krupko, V., Koynash, V., Ermakova, S.
doaj
UmojaNU Chapter of Phi Iota Alpha Fraternity, IncorporatedCHI ...
Boston University Howard Thurman Center for Common Ground
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Investigating the Bank-Lending Channel in South Africa: A VAR Approach [PDF]
The monetary policy transmission mechanism can broadly be categorised into three separate channels: the interest rate channel, the credit channel and the other asset price channel.
Kirsten L. Ludi, Marc Ground
core

