Results 81 to 90 of about 364,378 (309)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Obstacle-navigation control for a mobile robot suspended on overhead ground wires
This paper presents an obstacle-navigation control strategy for a mobile robot suspended on overhead ground wires of power transmission lines based on a novel movement mechanism The kinematics of the mobile robot and the process of obstacle-navigation ...
Fang LJ(房立金) +2 more
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Controlling Slab Flatness Automatically Using Laser Scanning and BIM
Developments of Terrestrial Laser Scanning (TLS) and Building Information Modeling (BIM) offer great opportunities to achieve a leap forward in the efficiency and completeness of dimensional control operations.
Bosché, Frédéric +3 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Every year, unmanned aircraft systems are increasingly used in both the civilian and military spheres. Stable communication with an unmanned aerial vehicle is provided by high-precision pointing of the antenna of the ground control point. In the automatic tracking mode of an unmanned aerial vehicle, the antenna guidance is carried out by the automatic ...
V. V. Vortnikov +2 more
openaire +4 more sources
Ground-based telescope pointing and tracking optimization using a neural controller
Neural network models (NN) have emerged as important components for applications of adaptive control theories. Their basic generalization capability, based on acquired knowledge, together with execution rapidity and correlation ability between input stimula, are basic attributes to consider NN as an extremely powerful tool for on-line control of ...
D. Mancini +2 more
openaire +4 more sources
A method for rough terrain locomotion based on Divergent Component of Motion
—For humanoid robots to be used in real world scenarios, there is a need of robust and simple walking controllers. Limitation to flat terrain is a drawback of many walking controllers.
Albu-Schäffer, Alin Olimpiu +2 more
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source

