Results 71 to 80 of about 11,322,797 (240)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Experimental Investigation of Snow Cloud Evolution During Helicopter Operations over Snow-Covered Surfaces

Aerospace
Helicopter operations over snow-covered surfaces are susceptible to whiteout conditions, which can severely degrade pilot visibility and threaten flight safety.
Tianshuang Shao, Wenkai Yu, Xiangnan Liu, Shi Liu, Zheng Yang, Yuntong Li   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Stable Near-Ground Hovering and Grasping with Rotary-Wing UAVs Equipped with Flexible Manipulators: A Review

Drones
As unmanned aerial vehicle (UAV) missions expand from aerial inspection and environmental sensing to physical interaction and autonomous manipulation, rotary-wing UAVs equipped with flexible manipulators offer a promising platform for contact-rich ...
Pengcheng Duan, Yueneng Yang, Yunbao Fan, Xiangen Tang   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Aircraft Wake-Vortex Evolution in Ground Proximity: Analysis and Parameterization [PDF]

, 2006
Field measurement data of 282 wake vortex pairs and respective environmental conditions acquired at Frankfurt Airport by means of lidar, Sodar/RASS, and ultrasonic anemometer are used to analyze wake vortex behavior in ground proximity. Exceptional cases
Steen, Meiko, Frank Holzäpfel, Meiko Steen, Holzäpfel, Frank   +3 more
core   +1 more source

Study on the Hydrodynamics of a Cownose Ray’s Flapping Pectoral Fin Model near the Ground

Journal of Marine Science and Engineering
Cownose rays typically swim close to the ocean floor, and the nearby substrate inevitably influences their swimming performance. In this research, we numerically investigate the propulsive capability of cownose rays swimming near the ground by resolving ...
Yang Luo, Zhexing Hou, Dongyang Chen, Tongshi Xu, Qiaogao Huang, Pengcheng Ye, Guang Pan   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Ground Effects and Stability Analysis of Airfoil Accelerated by Electromagnetic Propulsion

气体物理
Aerospace vehicle launched by electromagnetic propulsion is a potential option for future reusable space transportation systems. Complex ground effects and stability issues are induced generally due to the introduction of electromagnetic levitation force.
Xingdong LUO, Zihao HOU, Shaowei LI, Jinglong BO, Maochun ZHAI   +4 more
doaj   +1 more source

Numerical investigation on the aerodynamic efficiency of bio-inspired corrugated and cambered airfoils in ground effect. [PDF]

Sci Rep, 2022
Abdizadeh GR, Farokhinejad M, Ghasemloo S.   +2 more
europepmc   +1 more source