Results 91 to 100 of about 11,572,657 (308)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Applied SciencesThe measurements of rotational and translational seismic signals were carried out at the Imielin and Planetarium stations located in the central part of the Upper Silesian Coal Basin, Southern Poland.
Dariusz Nawrocki +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
AtmosphereIn order to explore the variation law and causes of the humidity effect of local water bodies, this paper selects the data of encrypted automatic weather stations (encrypted stations) and national conventional meteorological stations (conventional ...
Kai Liu +3 more
doaj +1 more source
Ground-state ferrimagnetism and magneto-caloric effects in Nd2NiMnO6
Materials Research Express, 2019 Extending our earlier investigation of magnetic properties of Nd _2 NiMnO _6 , we show that it exhibits a magnetic transition below ∼6 K to a ferrimagnetic state.
Ranjan Das +3 more
doaj +1 more source
Improving the Scalability of SOI-Based Tunnel FETs Using Ground Plane in Buried Oxide
IEEE Journal of the Electron Devices Society, 2019 Tunnel field-effect transistors (TFETs) are known to exhibit degraded electrical characteristics at smaller channel lengths, primarily due to direct source-to-drain band-to-band tunneling (BTBT).
Shelly Garg, Sneh Saurabh
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Grid Matrix-Based Ground Risk Map Generation for Unmanned Aerial Vehicles in Urban Environments
DronesAs a novel mode of urban air mobility (UAM), unmanned aerial vehicles (UAVs) pose a great amount of risk to ground people. Assessing ground risk and mitigation effects correctly is a focused issue.
Yuanjun Zhu +4 more
doaj +1 more source