Results 91 to 100 of about 707,618 (318)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Ground Viscous Effect on 3D Flow Structure of a Compound Wing-in-Ground Effect

open access: yesInternational Journal of Automotive and Mechanical Engineering, 2014
The wing-in-ground-effect craft is a new means for traveling on rivers, lakes, and at sea between islands. In this study, the effect of boundary layers due to the ground viscous effect on the aerodynamic coefficients of the compound wing of a WIG craft was numerically investigated.
Jamei, Saeed   +5 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Mechanisms of common ground in case-based web discussions in teacher education [PDF]

open access: yes, 2002
Previous studies suggest that before the participants in Web-based conferencing can reach deeper level interaction and learning, they have to gain an adequate level of common ground in terms of shared mutual understanding, knowledge, beliefs, assumptions,
Leinonen, Piritta   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Influence of Site Effects on Scaling Relation Between Rotational and Translational Signals Produced by Anthropogenic Seismicity

open access: yesApplied Sciences
The measurements of rotational and translational seismic signals were carried out at the Imielin and Planetarium stations located in the central part of the Upper Silesian Coal Basin, Southern Poland.
Dariusz Nawrocki   +3 more
doaj   +1 more source

The direct boundary element method: 2D site effects assessment on laterally varying layered media (methodology)

open access: yes, 2004
The Direct Boundary Element Method (DBEM) is presented to solve the elastodynamic field equations in 2D, and a complete comprehensive implementation is given. The DBEM is a useful approach to obtain reliable numerical estimates of site effects on seismic
Sánchez-Sesma, Francisco José   +7 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Effects of mining subsidence observed by time-lapse seismic reflection profiling [PDF]

open access: yes, 1995
Extracting coal from underground mineworkings causes the overlying rocks to subside with associated changes in the stress regime. The aim of the study reported here was to apply the surface seismic reflection method to study the effect of subsidence on ...
Al-Rawahy, Salim Y.S.
core  

Ground spider communities in experimentally disturbed Mediterranean woodland habitats

open access: yes, 2011
The protected Mediterranean woodland habitats in Israel are undergoing tree encroachment, resulting in loss of open patches with herbaceous vegetation. We suggested that this process results in a ground spider community dominated by shade-loving species.
Lubin, Yael   +6 more
core   +1 more source

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