Results 91 to 100 of about 229,035 (308)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Genesis and distribution of secondary porosity in the deep horizon of Gaoliu area, Nanpu Sag

Petroleum Exploration and Development, 2008
Strong dissolution generated a secondary porosity interval between 3 250–3 800 m in deep sandstones of the Shahejie Formation in Gaoliu area. The porosities included secondary intraparticle porosity, interparticle porosity, moldic porosity, and dissolved
Wen-cai ZHANG, He LI, Hui-jun LI, Yuan-lin MENG, Feng-bo YANG   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Ground deformation and source geometry of the 30 October 2016 Mw 6.5 Norcia earthquake (Central Italy) investigated through seismological data, DInSAR measurements, and numerical modelling [PDF]

, 2018
We investigate the Mw 6.5 Norcia (Central Italy) earthquake by exploiting seismological data, DInSAR measurements, and a numerical modelling approach. In particular, we first retrieve the vertical component (uplift and subsidence) of the displacements ...
Bignami, Christian, Carminati, Eugenio Ambrogio Maria, Castaldo, Raffaele, De Luca, Claudio, De Novellis, Vincenzo, Doglioni, Carlo, Lanari, Riccardo, Pepe, Susi, Petricca, Patrizio, Solaro, Giuseppe, Tizzani, Pietro, Valerio, Emanuela   +11 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Application of Machine Learning in Fault Detection And Classification in Power Transmission Lines

Journal of Innovation Information Technology and Application
Electrical faults have been identified as a significant contributing factor to electrical equipment damage. Such incidents can potentially result in a range of adverse consequences, including bushfires, electrical outages, and power shortages.
Michel Evariste Tshodi, Nathanael Kasoro, Freddy Keredjim, ALbert Ntumba Nkongolo, Jean-Jacques Katshitshi Matondo, Paul Mbuyi Balowe, Laurent Kitoko   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Analysis and Countermeasures for EMU Traction Motor Stator Insulation Faults

Chengshi guidao jiaotong yanjiu
[Objective] To ensure the reliability of the stator insulation in EMU (electric multiple unit) traction motors during stator manufacturing or maintenance, it is necessary to conduct tests such as ground insulation withstand voltage, interphase withstand ...
Chunlong NA, Hui PENG, Yulong WANG
doaj   +1 more source

Geometry optimization of dry ice blasting nozzle for the noise reduction using experimental validation [PDF]

, 2019
Dry ice blasting provides many advantages to surface cleaning in which the blasting medium sublimate during the surface impact will not leave a secondary contamination.
Mat, Mohamad Nur Hidayat
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source