Results 101 to 110 of about 2,858,375 (353)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Application of Machine Learning in Fault Detection And Classification in Power Transmission Lines

Journal of Innovation Information Technology and Application
Electrical faults have been identified as a significant contributing factor to electrical equipment damage. Such incidents can potentially result in a range of adverse consequences, including bushfires, electrical outages, and power shortages.
Michel Evariste Tshodi, Nathanael Kasoro, Freddy Keredjim, ALbert Ntumba Nkongolo, Jean-Jacques Katshitshi Matondo, Paul Mbuyi Balowe, Laurent Kitoko   +6 more
doaj   +1 more source

One-man, self-contained CO2 concentrating system [PDF]

A program to design, fabricate, and test a 1-man, self-contained, electrochemical CO2 concentrating system is described. The system was designed with electronic controls and instrumentation to regulate performance, to analyze and display performance ...
Powell, J. D., Schubert, F. H., Wynveen, R. A.   +2 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Analysis and Countermeasures for EMU Traction Motor Stator Insulation Faults

Chengshi guidao jiaotong yanjiu
[Objective] To ensure the reliability of the stator insulation in EMU (electric multiple unit) traction motors during stator manufacturing or maintenance, it is necessary to conduct tests such as ground insulation withstand voltage, interphase withstand ...
Chunlong NA, Hui PENG, Yulong WANG
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Deterministic Seismic Hazard Analysis in Thailand using Active Fault Data

International Journal of Technology, 2016
To develop seismic design criteria for buildings, seismic hazard analysis is required to estimate the ground motion intensity with criteria such as peak ground acceleration (PGA).
Apichat Janpila, Piyawat Foytong, Anat Ruangrassamee, Natthapong Areemit   +3 more
doaj   +1 more source

Reduction of ground noise in the transmitter crowbar instrumentation system by the use of baluns and other noise rejection methods [PDF]

Electrical noise interference in the transmitter crowbar monitoring instrumentation system creates false sensing of crowbar faults during a crowbar firing.
Bhanji, A., Daeges, J.
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

A proposed test area for the spaceborne geodynamic ranging system [PDF]

Precise geodetic measurements are proposed in which an orbiting laser obtains intersite distance between retroreflectors 25 to 100 km apart on the ground.
Lowman, P. D., Jr.
core   +1 more source