Results 61 to 70 of about 229,035 (308)
Soils and FoundationsGround deformation on the Earth’s surface layer is strongly affected by the nonlinearity of geomaterials. However, the formation process of such deformation has yet to be described in a unified manner based on mechanics.
Eiji Yamada +2 more
doaj +1 more source
A Broad, Distributed Active Fault Zone Lies beneath Salt Lake City, Utah
The Seismic Record, 2021 Although the Wasatch fault is currently known to have a high-seismic hazard from motion along range-bounding faults, new seismic data reveal faulted and folded 13,000–30,000-yr-old Lake Bonneville strata beneath Salt Lake City (SLC).
Lee M. Liberty +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Applied SciencesThe ground-motion simulation of regional-specific earthquake scenarios is crucial for the seismic design of key facilities. Herein, we considered parameter uncertainty in ground-motion simulations and the impact of multiple faults when determining the ...
Jiangyi Li, Zhengfang Li, Bengang Zhou
doaj +1 more source
Short circuit study of fixed speed wind turbines with STATCOM in distribution networks [PDF]
, 2015 The increased penetration of wind farm in distribution networks has brought changes in the performance of the whole system. Such disadvantages when connecting one of these distributed generation sources is reduced voltage and power stability of the AC ...
Darwish, M, Naain, MM, Zobaa, AF
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Slip in the 2010–2011 Canterbury earthquakes, New Zealand [PDF]
, 2012 The 3rd September 2010 Mw 7.1 Darfield and 21st February 2011 Mw 6.3 Christchurch (New Zealand) earthquakes occurred on previously unknown faults. We use InSAR ground displacements, SAR amplitude offsets, field mapping, aerial photographs, satellite ...
Elliott, J.R. +7 more
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Constraints on fault and lithosphere rheology from the coseismic slip and postseismic afterslip of the 2006 M_w 7.0 Mozambique earthquake [PDF]
, 2012 The 2006 M_w 7.0 Mozambique (Machaze) normal-faulting earthquake ruptured an unusually steeply dipping fault plane (~75°). The amount of slip in the earthquake decreased from depths of ~10 km toward the surface, and this shallow slip deficit was at least
Bergman, Eric +2 more
core +1 more source