Results 71 to 80 of about 229,035 (308)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The application of Skylab imagery to analysis of fault tectonics and earthquake hazards in the Peninsular Ranges, southern California [PDF]

The author has identified the following significant results. Frame 114 of the Salton Sea area was studied in all bands to analyze the appearance of important faults.
Merifield, P. M.
core   +1 more source

Effects of carbon fibers on consumer products [PDF]

, 1980
The potential effects of carbon fibers on consumer products such as dishwashers, microwave ovens, and smoke detectors were investigated. The investigation was divided into two categories to determine the potential faults and hazards that could occur if ...
Lovett, C. D., Wise, R. A.
core   +1 more source

Dissolved noble gases and stable isotopes as tracers of preferential fluid flow along faults in the Lower Rhine Embayment, Germany [PDF]

, 2015
Groundwater in shallow unconsolidated sedimentary aquifers close to the Bornheim fault in the Lower Rhine Embayment (LRE), Germany, has relatively low δ2H and δ18O values in comparison to regional modern groundwater recharge, and 4He concentrations up to
A Mayer, A Schäfer, A Schäfer, AL Flint, B Marty, B Marty, BJ Mailloux, C Cassiat, CAJ Appelo, CM Bethke, D Wiprut, DK Solomon, DL Egholm, DN Dewhurst, E Griesshaber, ER Oxburgh, F Peeters, GC Rawling, H Hager, HA Kemna, J Lippmann, J Lippmann, J Lippmann-Pipke, JC Poole, JN Andrews, JR Fulljames, JT Kulongoski, JT Kulongoski, K. M. Hiscock, L Ma, L. P. Gumm, M Bickle, M Stute, M Stute, MA Chan, MC Castro, MC Castro, MC Castro, MC Geluk, N. Cremer, P. F. Dennis, PA Ziegler, R Kipfer, R Vaikmäe, S. Simon, SJ Roberts, SMV Gilfillan, T Torgersen, T Torgersen, T Torgersen, T Torgersen, T Wiersberg, U Beyerle, V Lavastre, V. F. Bense, VF Bense, VF Bense, VF Bense, VF Bense, VF Bense, W Aeschbach-Hertig, W Boenigk, WP Gardner, Y Sano, YV Dublyansky, Z Zhou   +65 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Research on Fault Stability in Junggar Basin Based on 3D Geological Modeling

Cejing jishu
The distribution characteristics of ground stress and fault stability are very important for horizontal well location deployment, drilling orientation and hydraulic fracturing design in complex areas.
XIONG Yuwei, ZHANG Yan, MA Jinyu, LI Zhe, LEI Cheng, SUN Wentie   +5 more
doaj   +1 more source

A Study of Symmetrical and Unsymmetrical Short Circuit Fault Analyses in Power Systems

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
In this study, thecommon symmetrical and unsymmetrical short circuit faults in power systems areanalyzed detailed. Unlike the similar studies in the literature, metallic faultconditions for unsymmetrical faults are also given in the paper additionally ...
Yılmaz Yıldırım, Faruk Yalçın
doaj   +1 more source

An Equivalent Calculation Method for Pole-to-Ground Fault Transient Characteristics of Symmetrical Monopolar MMC Based DC Grid

IEEE Access, 2020
The pole-to-ground fault is one of the most typical faults in modular multilevel converters (MMCs) based DC grid. Analyzing the transient characteristics of fault voltages and currents is of great significance for fault identification, configuration of ...
Jingqiu Yu, Zheren Zhang, Zheng Xu, Guoteng Wang   +3 more
doaj   +1 more source

High impedance fault location: Generalized extension for ground faults

International Journal of Electrical Power & Energy Systems, 2020
Abstract This paper presents an impedance-based method to estimate the fault location in transmission lines. The mathematical formulation uses a generalized equation for the estimation of the fault distance, which does not depend on the fault type, and its solution is obtained by the application of a least squares method.
J. Doria-Garcia, C. Orozco-Henao, L.U. Iurinic, Juan Diego Pulgarín-Rivera   +3 more
openaire   +1 more source

GTEX: An expert system for diagnosing faults in satellite ground stations [PDF]

A proof of concept expert system called Ground Terminal Expert (GTEX) was developed at The University of Akron in collaboration with NASA Lewis Research Center.
Durkin, John, Petrik, Edward J., Schlegelmilch, Richard F.   +2 more
core   +1 more source