Results 31 to 40 of about 32,501 (265)
On Ground Motion Intensity Indices
Earthquake Spectra, 2007 The characterization of strength of earthquake demands for seismic analysis or design requires the specification of a level of intensity. Numerous ground motion intensity indices that have been proposed over the years are being used for normalizing or scaling earthquake records regardless of their efficiency.
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Applied SciencesSeismic fragility curves, derived from ground motion data, are essential tools for predicting and assessing potential damage to structures during earthquakes.
Sangki Park +3 more
doaj +1 more source
Employing Nonlinear Response History Analysis of ASCE 7-16 on a Benchmark Tall Building [PDF]
Numerical Methods in Civil Engineering, 2019 ASCE 7-16 has provided a comprehensive platform for the performance-based design of tall buildings. The core of the procedure is based on nonlinear response history analysis of the structure subjected to recorded or simulated ground motions.
R. Rezaie +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Underground SpaceIt is important to ensure that deep underground structures can withstand the potential strongest earthquakes throughout their design life. To achieve this goal, in the seismic design of such structures, it is necessary to select the real ground motions ...
Wei Yu +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Earthquake Research Advances, 2021 Long-period structures (e.g. Isolated structures) tend to produce pseudo-resonance with low frequency components of long-period ground motions, resulting in the increase in damage.
Feiyan Li, Linjian Wang, Yingxiong Wu
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source