Results 51 to 60 of about 32,501 (265)

Ground Motion Simulation

open access: yes, 2018
Task2 (WG-T2) deliverable of the INGV-T3 Research Project 2015-2016 "HYbrid ground motion prediction equations for PSha purposes: the study case of souTHERn Italy". The HYPSTHER project is devoted to develop a methodological approach to retrieve ground motion prediction models for Southern Calabria and Sicily, based on the integration between recorded
Maria, D'Amico   +3 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Incorporating Intensity Distance Attenuation Into PLUM Ground‐Motion‐Based Earthquake Early Warning in the United States: The APPLES Configuration

open access: yesEarth's Future
We develop Attenuated ProPagation of Local Earthquake Shaking (APPLES), a new configuration for the United States West Coast version of the Propagation of Local Undamped Motion (PLUM) earthquake early warning (EEW) algorithm that incorporates attenuation
Jessie K. Saunders   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Exploring the Effect of Near-Field Ground Motions on the Fragility Curves of Multi-Span Simply Supported Concrete Girder Bridges

open access: yesInfrastructures
Investigating the impact of near-field ground motions on the fragility curves of multi-span simply supported concrete girder bridges is the main goal of this paper.
Hassan Soltanmohammadi   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Research on Elastic Displacement Response Spectra of Near fault Ground Motions

open access: yes工程科学与技术, 2008
:In order to study displacement based seismic design method of near fault ground motions, 30 earthquakes and 132 near fault ground motion records were selected as statistical samples. The elastic displacement response spectra formula of near fault ground
卢明奇
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Formation keeping of unmanned ground vehicles

open access: yesMATEC Web of Conferences, 2017
Controlling motions of an unmanned ground vehicle becomes more popular in real world practices. Its application is useful for household chores, military services, medical purposes, and industrial revolutions, etc.
Muangmin Kamonwan, Wanichanon Thanapat
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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