Results 51 to 60 of about 31,319 (265)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
InfrastructuresInvestigating the impact of near-field ground motions on the fragility curves of multi-span simply supported concrete girder bridges is the main goal of this paper.
Hassan Soltanmohammadi +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Research on Elastic Displacement Response Spectra of Near fault Ground Motions
工程科学与技术, 2008 :In order to study displacement based seismic design method of near fault ground motions, 30 earthquakes and 132 near fault ground motion records were selected as statistical samples. The elastic displacement response spectra formula of near fault ground
卢明奇
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Formation keeping of unmanned ground vehicles
MATEC Web of Conferences, 2017 Controlling motions of an unmanned ground vehicle becomes more popular in real world practices. Its application is useful for household chores, military services, medical purposes, and industrial revolutions, etc.
Muangmin Kamonwan, Wanichanon Thanapat
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
, 2018 Task2 (WG-T2) deliverable of the INGV-T3 Research Project 2015-2016 "HYbrid ground motion prediction equations for PSha purposes: the study case of souTHERn Italy". The HYPSTHER project is devoted to develop a methodological approach to retrieve ground motion prediction models for Southern Calabria and Sicily, based on the integration between recorded
Maria, D'Amico +3 more
openaire +1 more source
Effects of Spatially Varying Seismic Ground Motions and Incident Angles on Behavior of Long Tunnels
Advances in Civil Engineering, 2018 Seismic behavior of long circle tunnels is significantly influenced by the nature of input motion. This study, based on the 3D finite-element method (FEM), evaluates the effects of spatially varying seismic ground motions and uniform input seismic ground
Yundong Zhou +3 more
doaj +1 more source