Results 71 to 80 of about 32,501 (265)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Review of source models for reproducing and predicting strong motions by empirical Green's function method

open access: yesJapan Architectural Review
Short‐period ground motions from earthquakes are calculated by semiempirical methods such as the empirical Green's function method or the stochastic Green's function method.
Kazuo Dan
doaj   +1 more source

Permanent displacement of slopes under multi-point earthquake ground motions considering site effects

open access: yesYantu gongcheng xuebao
The nonlinear dynamic response of slope soils caused by seismic motion may lead to inconsistent time histories of seismic acceleration at different positions of a slope.
SONG Jian1, 2 , PAN Yuhang2, LU Zhuxi2, JI Jian1, 2, ZHANG Fei1, 2, GAO Yufeng1, 2
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Comparison between the Effects of Near- and Far-Fault Ground Motions on the Seismic Response of a Soil-Pile-Structure System [PDF]

open access: yesJournal of Structural and Construction Engineering, 2016
Ground motions recorded in near-fault sites, where the rupture propagates toward the site, are significantly different from those observed in far-fault regions.
Saeed Abbasi Karafshani   +2 more
doaj  

Incremental Dynamic Analysis of Mid-Rise Buildings with Buckling Restrained Brace Frame System under Pulse-Like Near-Fault Ground Motions [PDF]

open access: yesJournal of Rehabilitation in Civil Engineering
Buckling Restrained Braced Frames (BRBFs) are frequently utilized as seismic force-resisting systems due to their considerable ductility and energy dissipation capacity.
Yaghub Minaei   +2 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

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