Results 61 to 70 of about 31,319 (265)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
BuildingsThis paper focuses on the effect of soil–structure interaction (SSI) on the seismic response of high-rise RC frame–shear wall structures under far-field long-period ground motions. Elastic–plastic time–history analyses were performed using ABAQUS.
Ke Yang +6 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Enhancing Near-Fault Ground Motion Recognition Through ICEEMDAN Technology
工程科学与技术Near-fault ground motion represents an exceptionally hazardous seismic activity characterized by high-energy velocity pulses. These pulses rapidly input a substantial amount of seismic energy into structures, causing significant damage in a very short ...
Zhen LIU, Junlin LU, Xingliang MA
doaj
Evaluation of seismic parameters of steel moment resisting frames based on “FEMA P-695” under near-field rotated ground motion [PDF]
Journal of Structural and Construction Engineering, 2016 Behavior factor (R) is one of the seismic design parameters that considers nonlinear performance of structures during an earthquake. In most of the seismic design codes, behavior factor has been used for considering nonlinear performance of structures in
M. Gerami, A. H. Mashayekhi, N. Siahpolo
doaj
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Ground motion prediction equations based on simulated ground motions
, 2020 178
openaire +1 more source