Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A Study on the Range Equation Modeling for Multichannel Medium-Earth-Orbit SAR-GMTI Systems
This paper studies the range equation modeling of a ground moving target for multichannel medium-Earth-orbit (MEO) synthetic aperture radar (SAR) ground moving target indication (GMTI), an issue which is challenging to tackle due to the non-linear motion
Yongkang Li +3 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
An Efficient SAR Ground Moving Target Refocusing Method Based on PPFFT and Coherently Integrated CPF
The problem of ground moving target imaging and detection is difficult due to the large range cell migration (RCM) and time-varying Doppler frequency migration (DFM) in synthetic aperture radar (SAR) system.
Dong Li +5 more
doaj +1 more source
Moving Target Shadow Analysis and Detection for ViSAR Imagery
The video synthetic aperture radar (ViSAR) is a new application in radar techniques. ViSAR provides high- or moderate-resolution SAR images with a faster frame rate, which permits the detection of the dynamic changes in the interested area.
Zhihua He +5 more
doaj +1 more source
Dual-Platform GMTI: First Results With The TerraSAR-X/TanDEM-X Constellation [PDF]
First ground moving target indication (GMTI) and parameter estimation results obtained with the German TerraSAR-X/TanDEM-X radar satellite constellation are presented and discussed.
Baumgartner, Stefan V., Krieger, Gerhard
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Ground-Target Recognition Method Based on Transfer Learning
A moving ground-target recognition system can monitor suspicious activities of pedestrians and vehicles in key areas. Currently, most target recognition systems are based on devices such as fiber optics, radar, and vibration sensors.
Qiuzhan Zhou +5 more
doaj +1 more source
Ground moving target-detection and focusing imaging under strong noise background
This study proposes a detection algorithm for a three-channel SAR system with weak ground moving target (GMT)-detection and focusing imaging under strong noise background.
Yang Zhou +4 more
doaj +1 more source

