Results 71 to 80 of about 2,000,383 (303)
Progressive Failure and Fracture Mechanism of Sandstone under Hydraulic-Mechanical Coupling
Shock and Vibration, 2020 Hydraulic coupling often leads to progressive rock failure accidents. Mechanical tests were performed over a range of combined pore water pressure and confining pressure stress path conditions to study the progressive failure characteristics of sandstone
Yingming Li +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Applied SciencesBased on the engineering problem of large deformation and support failure in the roadway of Ronghua No. 1 Mine, on-site in situ stress testing was carried out to understand the distribution characteristics of the in situ stress around the roadway.
Shulin Liu +6 more
doaj +1 more source
Investigation of the aerodynamic characteristics of a lifting body in ground proximity [PDF]
, 2016 The use of cambered hull shapes in the next generation of lighter-than-air vehicles to enhance aerodynamic performance, together with optimized take-off manoeuvre profiles, will require a more detailed understanding of ground proximity effects for such
Garry, Kevin P. +2 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Thermal expansion and effect of pressure on superconductivity in CuxTiSe2
, 2007 We report measurements of thermal expansion on a number of polycrystalline CuxTiSe2 samples corresponding to the parts of x - T phase diagram with different ground states, as well as the pressure dependence of the superconducting transition temperature ...
Bud'ko, S. L. +4 more
core +1 more source
, 2017 Honeycomb iridates such as $\gamma$-Li$_2$IrO$_3$ are argued to realize Kitaev spin-anisotropic magnetic exchange, along with Heisenberg and possibly other couplings.
Analytis, James G. +6 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Thrust-reverser flow investigation on a twin-engine transport [PDF]
An investigation was conducted in the NASA Langley 14 x 22 foot Subsonic Tunnel to study the effects of engine thrust reversing on an aft-mounted twin-engine transport and to develop effective testing techniques.
Gatlin, Gregory M., Quinto, P. Frank
core +1 more source