Results 41 to 50 of about 817,624 (304)

An investigation into the cause of the inner dark areas and outer lighter areas (ghosting) seen in dynamically-created two-dimensional bare footprints [PDF]

, 2017
Dynamic bare footprints differ from static bare footprints through the presence of additional, lighter markings around the rear of the heel print and apices of the toe print areas.
Reel, Sarah, Reidy, Selina, Simmonite, Neil, Vernon, Wesley   +3 more
core   +1 more source

Design and Manufacture of an Attachment Fitting for Transtibial Prosthetic Sockets Using Selective Laser Sintering [PDF]

, 2004
The focus of this work is using selective laser sintering to manufacture transtibial prosthetics sockets with compliant features to relieve contact pressure in sensitive areas.
Burhan, Danny, Crawford, Richard
core   +1 more source

Experimental estimation of energy absorption during heel strike in human barefoot walking. [PDF]

PLoS ONE, 2018
Metabolic energy expenditure during human gait is poorly understood. Mechanical energy loss during heel strike contributes to this energy expenditure. Previous work has estimated the energy absorption during heel strike as 0.8 J using an effective foot ...
Patricia M Baines, A L Schwab, A J van Soest   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Ground reaction forces during double limb stances while walking in individuals with unilateral transfemoral amputation

Frontiers in Bioengineering and Biotechnology, 2023
The asymmetrical gait of individuals with unilateral transfemoral amputation has been well documented. However, there is not a wealth of investigation into asymmetries during the double limb stance depending on whether the intact or prosthetic limb is ...
Toshiki Kobayashi, Mark W. P. Koh, Abu Jor, Abu Jor, Genki Hisano, Genki Hisano, Genki Hisano, Hiroto Murata, Daisuke Ichimura, Hiroaki Hobara   +9 more
doaj   +1 more source

Estimating Ground Reaction Forces From Inertial Sensors

IEEE Transactions on Biomedical Engineering
Accepted for publication at IEEE Transactions on Biomedical ...
B. Song, M. Paolieri, H. E. Stewart, L. Golubchik, J. L. McNitt-Gray, V. Misra, D. Shah   +6 more
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Quadriceps force and anterior tibial force occur obviously later than vertical ground reaction force: a simulation study

BMC Musculoskeletal Disorders, 2017
Background Although it is well known that quadriceps force generates anterior tibial force, it has been unclear whether quadriceps force causes great anterior tibial force during the early phase of a landing task.
Ryo Ueno, Tomoya Ishida, Masanori Yamanaka, Shohei Taniguchi, Ryohei Ikuta, Mina Samukawa, Hiroshi Saito, Harukazu Tohyama   +7 more
doaj   +1 more source