Results 51 to 60 of about 817,624 (304)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Coefficients of variation of ground reaction force measurement in cats. [PDF]
PLoS ONE, 2017 Gait analysis has been extensively performed in dogs and horses; however, very little is known about feline biomechanics. It was, therefore, the aim of this study to determine the coefficient of variation (CV) among three ground reaction force (GRF ...
Eva Schnabl-Feichter +2 more
doaj +1 more source
Force Plate with Simple Mechanical Springs and Separated Noncontact Sensor Elements
Sensors, 2021 This paper reports on a force plate (FP) using mechanical springs and noncontact distance sensors. The ground reaction force (GRF) is one of the factors for clarify biomechanics, and FPs are widely used to measure it.
Yuta Kawasaki +2 more
doaj +1 more source
Kinetic Quantification of Plyometric Take Off, Flight, and Landing Characteristics [PDF]
, 2010 This study assessed the kinetic characteristics of a variety of plyometric exercises and assessed gender differences therein. Twenty-six men and 23 women performed a variety of plyometric exercises including line hops, 15.24 cm cone hops, squat jumps ...
Ebben, William +5 more
core +2 more sources
, 2011 Background: A Sit to Stand task following a hip fracture may be achieved through compensations (e.g. bilateral arms and uninvolved lower extremity), not restoration of movement strategies of the involved lower extremity.
Bukata, Susan V. +3 more
core +1 more source
Effect of a unilateral hind limb orthotic lift on upper body movement symmetry in the trotting horse [PDF]
, 2018 In trotting horses, movement asymmetry is associated with ground reaction force asymmetry. In humans, limb length differences influence contralateral force production. Here we investigate whether horses, in immediate reaction to limb length changes, show
Deblanc, D, Pfau, T, Rhodin, M, Vertz, J
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Towards a footwear design tool : Influence of shoe midsole properties and ground stiffness on the impact force during running [PDF]
, 2009 International audienceSeveral spring-damper-mass models of the human body have been developed in order to reproduce the measured ground vertical reaction forces during human running (McMahon and Cheng, 1990; Ferris and Farley, 1999; Liu and Nigg, 2000 ...
Alaoui, Amina +3 more
core +5 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Quantifying the onset of the concentric phase of the force–time record during jumping [PDF]
, 2009 Thirteen college students performed a drop jump from height equal to their peak vertical jump, single leg jumps from the left and right legs, and a counter movement jump.
Ebben, William +4 more
core +2 more sources