Results 41 to 50 of about 2,805,359 (264)

Selective Membrane Transport Systems studied by Solid-State NMR Spectroscopy [PDF]

, 2009
Membranes border cells from their environment. Thus, they belong to the basic prerequisites for life as we know it. Within cells, membranes are used to establish compartments dedicated to specific tasks such as providing local proximity of components ...
Ader, C., NMR Spectroscopy, NMR-spectroscopie, Sub NMR Spectroscopy   +3 more
core   +1 more source

CO measurements from the ACE-FTS satellite instrument: data analysis and validation using ground-based, airborne and spaceborne observations [PDF]

, 2007
The Atmospheric Chemistry Experiment (ACE) mission was launched in August 2003 to sound the atmosphere by solar occultation. Carbon monoxide (CO), a good tracer of pollution plumes and atmospheric dynamics, is one of the key species provided by the ...
Emmons, Louisa, Rinsland, Curtis, Urban, J., E. Mahieu, J. Hannigan, S. Turquety, T. Borsdorff, De Mazière, Martine, Hase, Frank, Stiller, Gabrielle, Schneider, M., Wiacek, A., E. Le Flochmoën, Pazmino, Andrea, M. Coffey, Wiacek, Aldona, N. J. Livesey, Zafra, R. de, Barret, B., J. Drummond, Urban, Jakub, Cammas, Jean-Pierre, R. de Zafra, B. Funke, Walker, Kaley A., Robert, Cédric,, Catoire, Valéry, Catoire, V., Senten, Cindy, Walker, Kaley, Strong, Kimberley, Barret, Brice, A. Pazmino, Y. Kasai, V. Thouret, A. Kagawa, Walker, K.A., Clerbaux, Cathy, M. Höpfner, C. Clerbaux, P.-F. Coheur, Schneider, M, Coheur, P.-F., P. Nédélec, Strandberg, Anders,, Griffith, D.W.T., M. Luo, C. P. Rinsland, R. Sussmann, de Zafra, Robert, Le Flochmoën, E., Murtagh, D., Rinsland, C. P., Höpfner, M., P. Ricaud, Deeter, Merritt, Drummond, James, Clerbaux, Catherine, Hannigan, J., C. Robert, N. Jones, B. Barret, Coheur, P. -F., Funke, Bernd, Eddounia, Fadoua, Kramer, I., N\ue9d\ue9lec, Ph., Jones, Nick, Strandberg, Anders, D. Murtagh, Coheur, Pierre-François, Livesey, N.J., Robert, C., Pumphrey, Hugh, C. Senten, M. López-Puertas, Edwards, David P., Urban, Joachim, Robert, Claude, Hannigan, James W., Dupuy, Eric, I. Kramer, Boone, C., De Maziere, M., Deeter, M., Turquety, Solène, D. P. Edwards, Mahieu, E., Duchatelet, P., Griffith, D. W. T., Dupuy, E., Pumphrey, H., Nédélec, Ph., C. Boone, Mazière, M. De, Hoepfner, Michael, Cammas, J.P., Edwards, D. P., Hannigan, Jim, Murtagh, Donal,, Mahieu, Emmanuel, López-Puertas, M., Sussmann, Ralf, P. Bernath, Sussmann, R., Drummond, J., Le Flochmo\uebn, E., J. Gille, Mazi\ue8re, M. De, Strong, K., Bernath, P., Rinsland, C.P., Urban, Joachim,, Boone, Chris, Kramer, Isabell, F. Eddounia, Eddounia, F., Duchatelet, Pierre, George, M., Coffey, M., M. De Mazière, Hoepfner, M., Kasai, Y., Stiller, G., Höpfner, Michael, A. Wiacek, M. Deeter, Murtagh, Donal, Edwards, David, Kagawa, Akiko, L. Emmons, Walker, K. A., A. Strandberg, Borsdorff, T., M. Schneider, K. Strong, Jones, N., Ricaud, P., Strong, Kimberly, Schneider, Matthias, Hase, F., Bernath, Peter, Cammas, J. P., G. Stiller, Thouret, V., M. George, V. Catoire, Urban, Jo, de Zafra, R., K. A. Walker, Ricaud, Philippe, Turquety, S., L\uf3pez-Puertas, M., Thouret, Valérie, Emmons, L., H. Pumphrey, J. Urban, H\uf6pfner, M., George, Michael, J. P. Cammas, Robert, Cédric, Robert, P. Duchatelet, Murtagh, Donal P., Jones, Nicholas, Coheur, Pierre, D. W. T. Griffith, George, Maya, Boone, Christopher D., Kagawa, A., Rinsland, Curtis P., Gille, J., Funke, B., Livesey, N. J., Lopez-Puertas, Manuel, Griffith, Dave W. T., Clerbaux, C., Luo, M., Borsdorff, Tobias, E. Dupuy, Nedelec, P., Strandberg, A., Coheur, P. F., Pazmino, A., F. Hase, Senten, C., Edwards, D.P.   +185 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Application of Infrared Spectroscopy in Microalgal Research

, 2019
Microalgae are rich in carotenoids, vitamins, proteins, polyunsaturated fatty acids and other nutrients required by humans and animals. In addition, some microalgae also play critical roles in aquatic ecological environment.
Liu Jing-hua, Qin Song, Qi Ze-ming, Huang Qing, Chen Jun   +4 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

NMR characterization of foldedness for the production of E3 RING domains [PDF]

, 2010
We summarize the use of NMR spectroscopy in the production and the screening of stability and foldedness of protein domains, and apply it to the RING domains of E3 ubiquitin-ligases.
NMR Spectroscopy, Folkers, G.E., Huang, A., Sub NMR Spectroscopy, Boelens, R., Dep Scheikunde, de Jong, R.N.   +6 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source