Results 171 to 180 of about 4,316,417 (322)

Mathematical Analysis of a Generalized Chiral Quark Soliton Model

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2006
A generalized version of the so-called chiral quark soliton model (CQSM) in nuclear physics is introduced. The Hamiltonian of the generalized CQSM is given by a Dirac type operator with a mass term being an operator-valued function.
Asao Arai
doaj  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Fractional minimization problem on the Nehari manifold

open access: yesElectronic Journal of Differential Equations, 2018
In the framework of fractional Sobolev space, using Nehari manifold and concentration compactness principle, we study a minimization problem in the whole space involving the fractional Laplacian.
Mei Yu, Meina Zhang, Xia Zhang
doaj  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Hierarchical ground-state crystals underlying Hertzian quasicrystals. [PDF]

open access: yesNat Commun
Li Y   +5 more
europepmc   +1 more source

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