Results 21 to 30 of about 3,929,644 (181)

Collective Excitations and Ground State Correlations

, 1994
A generalized RPA formalism is presented which treats pp and ph correlations on an equal footing. The effect of these correlations on the single-particle Green function is discussed and it is demonstrated that a self-consistent treatment of the single ...
Anastasio, Baym, Boersma, Brandow, Brockmann, Brown, Celenza, Coester, Day, Dickhoff, E. Heinz, Ellis, Fantoni, Fritz, H. Müther, H.A. Mavromatis, Jing, Kümmel, Machleidt, Martin, Mavromatis, Mavromatis, Müther, Müther, Müther, Müther, Pandharipande, Pieper, Schmid, Serot, Song, ter Haar, Thouless, Yang   +33 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Mimicking Time Evolution within a Quantum Ground State: Ground-State Quantum Computation, Cloning, and Teleportation

, 2003
Ground-state quantum computers mimic quantum mechanical time evolution within the amplitudes of a time-independent quantum state. We explore the principles that constrain this mimicking. A no-cloning argument is found to impose strong restrictions. It is
A. Ekert, Ari Mizel, L. K. Grover, M. A. Nielsen, P. W. Shor, R. Jozsa, R. P. Feynman   +6 more
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Improved Quantum Hard-Sphere Ground-State Equations of State

, 2007
The London ground-state energy formula as a function of number density for a system of identical boson hard spheres, corrected for the reduced mass of a pair of particles in a sphere-of-influence picture, and generalized to fermion hard-sphere systems ...
A. L. Fetter, C. A. Rogers, F. London, G. A. Baker, Jr., G. D. Scott, George A. Baker, J. W. Clark, M. A. Solís, M. A. Solís, M. de Llano, N. J. A. Sloan, W. Lenz   +11 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

A Model Ground State of Polyampholytes

, 1998
The ground state of randomly charged polyampholytes is conjectured to have a structure similar to a necklace, made of weakly charged parts of the chain, compacting into globules, connected by highly charged stretched `strings'.
A. J. Guttmann, A. V. Dobrynin, A. Y. Grosberg, B. Derrida, B. Derrida, B. Derrida, B. Derrida, C. Tanford, D. Bratko, D. Dhar, D. Ertaş, D. Ertaş, G. F. Lawler, G. F. Lawler, G. F. Lawler, J. Wittmer, L. D. Landau, L. Frachebourg, P. G. de Gennes, P. G. Higgs, R. E. Bradley, S. F. Edwards, Shay Wolfling, T. E. Creighton, Y. Kantor, Y. Kantor, Y. Kantor, Y. Kantor, Y. Kantor, Y. Kantor, Y. Kantor, Yacov Kantor   +31 more
core   +1 more source

Towards the Ground State of the Supermembrane [PDF]

, 2012
The explicit, near the origin, form of the ground state of the SU(2) supermembrane matrix model is studied. We evaluate the 2nd order terms of the Taylor expansion of the wave-function, which together with the 0th and the 1st order terms can be used to ...
Banks, Claudson, de Wit, de Wit, Erdös, Flume, Fröhlich, Gran, Halpern, Hasler, Hoppe, Hoppe, Hoppe, Hynek, Maciej Trzetrzelewski, Michishita, Michishita, Nicolai, Porrati, Sethi, Smilga, Trzetrzelewski, Wosiek, Yi, Yoji Michishita   +24 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source