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Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ground state solution for Schrödinger-Choquard equation: doubly critical case

open access: yesBoundary Value Problems
In this paper, we investigate the following Schrödinger-Choquard equation: − Δ u + u = ( I α ∗ | u | 2 α ♯ ) | u | 2 α ♯ − 2 u + | u | q − 2 u + | u | r − 2 u , x ∈ R N , $$ -\Delta u+u = (I_{\alpha }*|u|^{2_{\alpha }^{\sharp }})|u|^{2_{\alpha }^{ \sharp
Yusheng Shen, Zhiwei Zou, You Gao
doaj   +1 more source

Homoclinic solutions for second-order Hamiltonian systems with periodic potential

open access: yesBoundary Value Problems, 2018
In this paper, we study the second-order Hamiltonian systems u¨−L(t)u+∇W(t,u)=0,t∈R, $$ \ddot{u}-L(t)u+\nabla W(t,u)=0,\quad t\in \mathbb{R}, $$ where L∈C(R,RN×N) $L\in C(\mathbb{R},\mathbb{R}^{N\times N})$ is a T-periodic and positive definite matrix ...
Yiwei Ye
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Ground state solution of a nonlocal boundary-value problem

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we apply the Nehari manifold method to study the Kirchhoff type equation $$ -\Big(a+b\int_\Omega|\nabla u|^2dx\Big)\Delta u=f(x,u) $$ subject to Dirichlet boundary conditions.
Cyril Joel Batkam
doaj  

Ground states for a class of asymptotically periodic Schrödinger–Poisson systems with critical growth

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2018
The purpose of this paper is to study the existence of ground state solution for the Schr\"{o}dinger–Poisson systems: \[\begin{cases} -\Delta u+V(x)u+K(x)\phi u=Q(x)|u|^{4}u+f(x,u),&x\in\mathbb{R}^{3},\\ -\Delta\phi=K(x)u^{2},&x\in\mathbb{R}^{3}, \end ...
Da-Bin Wang, Hua-Fei Xie, Wen Guan
doaj   +1 more source

Ground state solutions to nonlinear equations with p-Laplacian

open access: yesNonlinear Analysis, 2019
Ground state solutions are solutions \( u \) of some kind of equations such as the equation \[ \operatorname{div} (r(x)\left|\nabla u\right|^{p-2}\nabla u )+ q(x) F(u) = 0, p > 1,x\in \mathbb{R}^d, \] which are positive, minimize a certain energy functional, and satisfy \(\lim_{|x|\to\infty} u(x) = 0.\) In this paper the authors investigate the ...
Zuzana Došlá, Serena Matucci
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Existence of ground state solutions for a class of Choquard equations with local nonlinear perturbation and variable potential

open access: yesBoundary Value Problems, 2021
In this paper, we focus on the existence of solutions for the Choquard equation { − Δ u + V ( x ) u = ( I α ∗ | u | α N + 1 ) | u | α N − 1 u + λ | u | p − 2 u , x ∈ R N ; u ∈ H 1 ( R N ) , $$\begin{aligned} \textstyle\begin{cases} {-}\Delta {u}+V(x)u ...
Jing Zhang, Qiongfen Zhang
doaj   +1 more source

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