Results 51 to 60 of about 248,226 (264)

Ground state solutions for a fractional Schrödinger equation with critical growth [PDF]

open access: yesAsymptotic Analysis, 2017
In this paper we investigate the existence of nontrivial ground state solutions for the following fractional scalar field equation [Formula: see text] where [Formula: see text], [Formula: see text], [Formula: see text] is the fractional Laplacian, [Formula: see text] is a bounded potential satisfying suitable assumptions, and [Formula: see text] has ...
Vincenzo Ambrosio, Giovany M. Figueiredo
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Ground-state energies of the open and closed p + ip-pairing models from the Bethe Ansatz

open access: yesNuclear Physics B, 2018
Using the exact Bethe Ansatz solution, we investigate methods for calculating the ground-state energy for the p+ip-pairing Hamiltonian. We first consider the Hamiltonian isolated from its environment (closed model) through two forms of Bethe Ansatz ...
Yibing Shen, Phillip S. Isaac, Jon Links
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Asymptotic behavior of ground state solution for Henon type systems

open access: yesElectronic Journal of Differential Equations, 2010
In this article, we investigate the asymptotic behavior of positive ground state solutions, as $alphaoinfty$, for the following Henon type system $$ -Delta u=frac{2p}{p+q}|x|^alpha u^{p-1}v^q,quad -Delta v=frac{2q}{p+q}|x|^alpha u^pv^{q-1},quad hbox{
Ying Wang, Jianfu Yang
doaj  

Nonlinear dynamics as a ground-state solution on quantum computers

open access: yesPhysical Review Research
For the solution of time-dependent nonlinear differential equations, we present variational quantum algorithms (VQAs) that encode both space and time in qubit registers.
Albert J. Pool   +4 more
doaj   +1 more source

The Brezis–Nirenberg Problem for the Hénon Equation: Ground State Solutions [PDF]

open access: yesAdvanced Nonlinear Studies, 2012
Abstract This work is devoted to the Dirichlet problem for the equation −Δu = λu + |x|α|u| 2*−2 u in the unit ball of ℝ N . We assume that λ is bigger than the first eigenvalues of the laplacian, and we prove that there exists a ...
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Ground-state energy of a Richardson-Gaudin integrable BCS model

open access: yesSciPost Physics Core, 2020
We investigate the ground-state energy of a Richardson-Gaudin integrable BCS model, generalizing the closed and open p+ip models. The Hamiltonian supports a family of mutually commuting conserved operators satisfying quadratic relations.
Yibing Shen, Phillip S. Isaac, Jon Links
doaj   +1 more source

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