Results 71 to 80 of about 21,392,187 (250)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Explicit large nuclear charge limit of electronic ground states for Li, Be, B, C, N, O, F, Ne and basic aspects of the periodic table [PDF]

, 2009
This paper is concerned with the Schrödinger equation for atoms and ions with $N=1$ to 10 electrons. In the asymptotic limit of large nuclear charge $Z$, we determine explicitly the low-lying energy levels and eigenstates.
Goddard, BD, Friesecke, G., Friesecke, Gero, Friesecke, G, Goddard, B.D., Goddard, B. (Benjamin)   +5 more
core   +1 more source

Ground state sign-changing solution for a logarithmic Kirchhoff-type equation in $\mathbb{R}^{3}$

Electronic Journal of Qualitative Theory of Differential Equations
We investigate the following logarithmic Kirchhoff-type equation: \begin{equation*} \left(a+b\int_{\mathbb{R}^{3}}|\nabla u|^{2}+V(x)u^{2}dx\right)[-\Delta u+V(x)u]=|u|^{p-2}u\ln |u|,\qquad x\in\mathbb{R}^{3}, \end{equation*} where $a,b>0$ are constants,
Wei-Long Yang, Jia-Feng Liao
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Pesticides in Ground Water: Will the EPA's New Regulation Decrease Health Risks? [PDF]

The EPA's new regulation to protect ground water, the Pesticides and Ground Water Management Plan rule, will not significantly decrease health risks.
Moyle, Petrea R.
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Theoretical Proof of and Proposed Experimental Search for the Ground Triplet State of a Wigner-Regime Two-Electron ‘Artificial Atom’ in a Magnetic Field

Axioms
It is experimentally established that there is no ground triplet state of the natural He atom. There is also no exact analytical solution to the Schrödinger equation corresponding to this state.
Marlina Slamet, Viraht Sahni
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Structure of ground state solutions for singular elliptic equations with a quadratic gradient term

Electronic Journal of Differential Equations, 2011
We establish results on existence, non-existence, and asymptotic behavior of ground state solutions for the singular nonlinear elliptic problem $$displaylines{ -Delta u = g(u)| abla u |^2 + lambdapsi(x) f(u) quadhbox{in } mathbb{R}^N,\ u > 0 ...
Antonio Luiz Melo, Carlos Alberto Santos
doaj  

Existence of a ground-state solution for a quasilinear Schrödinger system

Frontiers in Physics
In this paper, we consider the following quasilinear Schrödinger system.−Δu+u+k2Δ|u|2u=2αα+β|u|α−2u|v|β,x∈RN,−Δv+v+k2Δ|v|2v=2βα+β|u|α|v|β−2v,x∈RN,where k < 0 is a real constant, α > 1, β > 1, and α + β < 2*.
Xue Zhang, Jing Zhang, Jing Zhang, Jing Zhang   +3 more
doaj   +1 more source