Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
State of Ohio technical guidance for sealing unused wells
, 1996 Title from cover of PDF document (viewed , 2006).; Includes bibliographical references (32-33).; Harvested from the web on 3/2 ...
Ohio. State Coordinating Committee on Ground Water.
core
Numerical method for the ground state solution of Logarithmic nonlinear Schrodinger equation
四川大学学报. 自然科学版, 2021 We construct a numerical method for computing the ground state solution of Logarithmic nonlinear Schrodinger equation. We firstly regularize the energy functional of the model and then compute the ground state solution by using the normalized gradient ...
FENG Zi-Xu, HE Wei-Qing, ZHANG Shi-Quan
doaj
Ground state solutions for asymptotically periodic fractional Choquard equations
Electronic Journal of Qualitative Theory of Differential Equations, 2019 This paper is dedicated to studying the following fractional Choquard equation \begin{equation*} (-\triangle)^s u+V(x)u=\left(\int_{\mathbb{R}^N}\frac{Q(y)F(u(y))}{|x-y|^\mu}\mathrm{d}y\right)Q(x)f(u), \qquad u\in H^s(\mathbb{R}^{N}), \end{equation*
Sitong Chen, Xianhua Tang
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Numerical modelling of ground borne vibrations from high speed rail lines on embankments [PDF]
, 2013 A three dimensional numerical model is presented capable of modelling the propagation and transmission of ground vibration in the vicinity of high speed railways.
Giannopoulos, A +5 more
core +1 more source
Ground state solutions for a quasilinear Kirchhoff type equation
Electronic Journal of Qualitative Theory of Differential Equations, 2016 We study the ground state solutions of the following quasilinear Kirchhoff type equation \[ -\left(1+b\int_{\mathbb{R}^{3}}|\nabla u|^2dx\right)\Delta u + V(x)u-[\Delta(u^2)]u=|u|^{10}u+\mu |u|^{p-1}u,\qquad x\in \mathbb{R}^3, \] where $b\geq 0$ and $\mu$
Hongliang Liu, Haibo Chen, Qizhen Xiao
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
State of Ohio technical guidance for well construction and ground water protection
, 2000 Title from PDF t.p. (viewed on Sept. 14, 2007).; At head of title: State of Ohio.; Includes bibliographical references (p.
Ohio. Well Construction Standards Workgroup.
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source